Unmasking a two-faced protein

Single-molecule fluorescence spectroscopy and molecular dynamics simulations illuminate the structure and dynamics of PSD-95, a protein involved in neural plasticity.

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Bibliographic Details
Published in:eLife 2022-10, Vol.11
Main Authors: Maslov, Ivan, Hendrix, Jelle
Format: Article
Language:English
Subjects:
Chemical bonds
Fluorescence spectroscopy
Insight
Ligands
Microscopy
Molecular dynamics
Neurons
Neuroplasticity
Neuroscience
Neurotransmission
postsynaptic density
Postsynaptic density proteins
protein dynamics
Proteins
Signal transduction
Simulation
Simulation methods
single molecule fluorescence
single-molecule FRET
Structural Biology and Molecular Biophysics
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Description
Summary:Single-molecule fluorescence spectroscopy and molecular dynamics simulations illuminate the structure and dynamics of PSD-95, a protein involved in neural plasticity.
ISSN:2050-084X
2050-084X
DOI:10.7554/eLife.83482