Loading…
Unmasking a two-faced protein
Single-molecule fluorescence spectroscopy and molecular dynamics simulations illuminate the structure and dynamics of PSD-95, a protein involved in neural plasticity.
Saved in:
Published in: | eLife 2022-10, Vol.11 |
---|---|
Main Authors: | , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | |
---|---|
cites | cdi_FETCH-LOGICAL-c511t-fae8a5be53c1d7a9e67f067e855243b4621d8fcd22ac8867aa8091dd03fcacc3 |
container_end_page | |
container_issue | |
container_start_page | |
container_title | eLife |
container_volume | 11 |
creator | Maslov, Ivan Hendrix, Jelle |
description | Single-molecule fluorescence spectroscopy and molecular dynamics simulations illuminate the structure and dynamics of PSD-95, a protein involved in neural plasticity. |
doi_str_mv | 10.7554/eLife.83482 |
format | article |
fullrecord | <record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_505ca1b844ee40039b7f30aa418fadc4</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A723233258</galeid><doaj_id>oai_doaj_org_article_505ca1b844ee40039b7f30aa418fadc4</doaj_id><sourcerecordid>A723233258</sourcerecordid><originalsourceid>FETCH-LOGICAL-c511t-fae8a5be53c1d7a9e67f067e855243b4621d8fcd22ac8867aa8091dd03fcacc3</originalsourceid><addsrcrecordid>eNptkt-LEzEQgBdR8DjvyWeh4Isirfm5SV-E4_C0UBD0BN_CbDJZU3c3Ndk9vf_etD3kVkweMky--UKGqarnlKyUlOItboPHleZCs0fVGSOSLIkW3x4_iJ9WFznvSFlKaE3XZ9WLr0MP-UcY2gUsxl9x6cGiW-xTHDEMz6onHrqMF_fneXVz_f7m6uNy--nD5upyu7SS0rHUoAbZoOSWOgVrrJUntUItJRO8ETWjTnvrGAOrda0ANFlT5wj3Fqzl59XmpHURdmafQg_pzkQI5piIqTWQxmA7NJJIC7TRQiAKQvi6UZ4TAEG1B2dFcb07ufZT06OzOIwJupl0fjOE76aNt2YtNZWsLoJX94IUf06YR9OHbLHrYMA4ZcMUqwVRnBzQl_-guziloXSqUJxIruVDqoXygTD4WN61B6m5VIwzzpnUhVr9hyrbYR9sHNCHkp8VvJ4VFGbE32MLU85m8-XznH1zYm2KOSf0f_tBiTkMjzkOjzkOD_8DKvK0Qg</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2730538506</pqid></control><display><type>article</type><title>Unmasking a two-faced protein</title><source>Publicly Available Content Database</source><source>PubMed Central</source><creator>Maslov, Ivan ; Hendrix, Jelle</creator><creatorcontrib>Maslov, Ivan ; Hendrix, Jelle</creatorcontrib><description>Single-molecule fluorescence spectroscopy and molecular dynamics simulations illuminate the structure and dynamics of PSD-95, a protein involved in neural plasticity.</description><identifier>ISSN: 2050-084X</identifier><identifier>EISSN: 2050-084X</identifier><identifier>DOI: 10.7554/eLife.83482</identifier><language>eng</language><publisher>Cambridge: eLife Science Publications, Ltd</publisher><subject>Chemical bonds ; Fluorescence spectroscopy ; Insight ; Ligands ; Microscopy ; Molecular dynamics ; Neurons ; Neuroplasticity ; Neuroscience ; Neurotransmission ; postsynaptic density ; Postsynaptic density proteins ; protein dynamics ; Proteins ; Signal transduction ; Simulation ; Simulation methods ; single molecule fluorescence ; single-molecule FRET ; Structural Biology and Molecular Biophysics</subject><ispartof>eLife, 2022-10, Vol.11</ispartof><rights>COPYRIGHT 2022 eLife Science Publications, Ltd.</rights><rights>2022, Maslov and Hendrix. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2022, Maslov and Hendrix 2022 Maslov and Hendrix</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c511t-fae8a5be53c1d7a9e67f067e855243b4621d8fcd22ac8867aa8091dd03fcacc3</cites><orcidid>0000-0001-5731-1297 ; 0000-0003-3371-4416</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2730538506/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2730538506?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids></links><search><creatorcontrib>Maslov, Ivan</creatorcontrib><creatorcontrib>Hendrix, Jelle</creatorcontrib><title>Unmasking a two-faced protein</title><title>eLife</title><description>Single-molecule fluorescence spectroscopy and molecular dynamics simulations illuminate the structure and dynamics of PSD-95, a protein involved in neural plasticity.</description><subject>Chemical bonds</subject><subject>Fluorescence spectroscopy</subject><subject>Insight</subject><subject>Ligands</subject><subject>Microscopy</subject><subject>Molecular dynamics</subject><subject>Neurons</subject><subject>Neuroplasticity</subject><subject>Neuroscience</subject><subject>Neurotransmission</subject><subject>postsynaptic density</subject><subject>Postsynaptic density proteins</subject><subject>protein dynamics</subject><subject>Proteins</subject><subject>Signal transduction</subject><subject>Simulation</subject><subject>Simulation methods</subject><subject>single molecule fluorescence</subject><subject>single-molecule FRET</subject><subject>Structural Biology and Molecular Biophysics</subject><issn>2050-084X</issn><issn>2050-084X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptkt-LEzEQgBdR8DjvyWeh4Isirfm5SV-E4_C0UBD0BN_CbDJZU3c3Ndk9vf_etD3kVkweMky--UKGqarnlKyUlOItboPHleZCs0fVGSOSLIkW3x4_iJ9WFznvSFlKaE3XZ9WLr0MP-UcY2gUsxl9x6cGiW-xTHDEMz6onHrqMF_fneXVz_f7m6uNy--nD5upyu7SS0rHUoAbZoOSWOgVrrJUntUItJRO8ETWjTnvrGAOrda0ANFlT5wj3Fqzl59XmpHURdmafQg_pzkQI5piIqTWQxmA7NJJIC7TRQiAKQvi6UZ4TAEG1B2dFcb07ufZT06OzOIwJupl0fjOE76aNt2YtNZWsLoJX94IUf06YR9OHbLHrYMA4ZcMUqwVRnBzQl_-guziloXSqUJxIruVDqoXygTD4WN61B6m5VIwzzpnUhVr9hyrbYR9sHNCHkp8VvJ4VFGbE32MLU85m8-XznH1zYm2KOSf0f_tBiTkMjzkOjzkOD_8DKvK0Qg</recordid><startdate>20221019</startdate><enddate>20221019</enddate><creator>Maslov, Ivan</creator><creator>Hendrix, Jelle</creator><general>eLife Science Publications, Ltd</general><general>eLife Sciences Publications Ltd</general><general>eLife Sciences Publications, Ltd</general><scope>AAYXX</scope><scope>CITATION</scope><scope>ISR</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0001-5731-1297</orcidid><orcidid>https://orcid.org/0000-0003-3371-4416</orcidid></search><sort><creationdate>20221019</creationdate><title>Unmasking a two-faced protein</title><author>Maslov, Ivan ; Hendrix, Jelle</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c511t-fae8a5be53c1d7a9e67f067e855243b4621d8fcd22ac8867aa8091dd03fcacc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Chemical bonds</topic><topic>Fluorescence spectroscopy</topic><topic>Insight</topic><topic>Ligands</topic><topic>Microscopy</topic><topic>Molecular dynamics</topic><topic>Neurons</topic><topic>Neuroplasticity</topic><topic>Neuroscience</topic><topic>Neurotransmission</topic><topic>postsynaptic density</topic><topic>Postsynaptic density proteins</topic><topic>protein dynamics</topic><topic>Proteins</topic><topic>Signal transduction</topic><topic>Simulation</topic><topic>Simulation methods</topic><topic>single molecule fluorescence</topic><topic>single-molecule FRET</topic><topic>Structural Biology and Molecular Biophysics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Maslov, Ivan</creatorcontrib><creatorcontrib>Hendrix, Jelle</creatorcontrib><collection>CrossRef</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Science Database</collection><collection>Biological Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>eLife</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Maslov, Ivan</au><au>Hendrix, Jelle</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Unmasking a two-faced protein</atitle><jtitle>eLife</jtitle><date>2022-10-19</date><risdate>2022</risdate><volume>11</volume><issn>2050-084X</issn><eissn>2050-084X</eissn><abstract>Single-molecule fluorescence spectroscopy and molecular dynamics simulations illuminate the structure and dynamics of PSD-95, a protein involved in neural plasticity.</abstract><cop>Cambridge</cop><pub>eLife Science Publications, Ltd</pub><doi>10.7554/eLife.83482</doi><orcidid>https://orcid.org/0000-0001-5731-1297</orcidid><orcidid>https://orcid.org/0000-0003-3371-4416</orcidid><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 2050-084X |
ispartof | eLife, 2022-10, Vol.11 |
issn | 2050-084X 2050-084X |
language | eng |
recordid | cdi_doaj_primary_oai_doaj_org_article_505ca1b844ee40039b7f30aa418fadc4 |
source | Publicly Available Content Database; PubMed Central |
subjects | Chemical bonds Fluorescence spectroscopy Insight Ligands Microscopy Molecular dynamics Neurons Neuroplasticity Neuroscience Neurotransmission postsynaptic density Postsynaptic density proteins protein dynamics Proteins Signal transduction Simulation Simulation methods single molecule fluorescence single-molecule FRET Structural Biology and Molecular Biophysics |
title | Unmasking a two-faced protein |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T21%3A42%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Unmasking%20a%20two-faced%20protein&rft.jtitle=eLife&rft.au=Maslov,%20Ivan&rft.date=2022-10-19&rft.volume=11&rft.issn=2050-084X&rft.eissn=2050-084X&rft_id=info:doi/10.7554/eLife.83482&rft_dat=%3Cgale_doaj_%3EA723233258%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c511t-fae8a5be53c1d7a9e67f067e855243b4621d8fcd22ac8867aa8091dd03fcacc3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2730538506&rft_id=info:pmid/&rft_galeid=A723233258&rfr_iscdi=true |