Metabolic syndrome in adults with autistic traits: associated psychological, behavioral, and biological factors in females and males - a PharmLines initiative

While cardiovascular diseases is highly prevalent and an important cause of mortality in autistic adults, knowledge on their increased cardiovascular risk is limited. Hence, this study aimed to investigate psychological, behavioral, and physical factors associated with metabolic syndrome (MetS) in a...

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Bibliographic Details
Published in:Frontiers in psychiatry 2023-12, Vol.14, p.1303840-1303840
Main Authors: Warreman, E B, Nooteboom, L A, Leenen, P J M, Geurts, H M, Terry, M B, Bos, J H J, Hak, E, Hoek, H W, van Rossum, E F C, Vermeiren, R R J M, Ester, W A
Format: Article
Language:English
Subjects:
adults
autism
autistic traits
cardiovascular risk
metabolic syndrome
Psychiatry
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Summary:While cardiovascular diseases is highly prevalent and an important cause of mortality in autistic adults, knowledge on their increased cardiovascular risk is limited. Hence, this study aimed to investigate psychological, behavioral, and physical factors associated with metabolic syndrome (MetS) in adults with autistic traits. In total, 17,705 adults from the Lifelines Cohort were included and categorized using Autism Spectrum Quotient-10 sum-scores. The quartiles with highest (HQ-traits-group females:  = 2,635; males:  = 1803) and lowest levels of autistic traits (LQ-traits-group,  = idem) were analyzed. Using multivariable logistic regression, the associations between MetS and (self-reported and interviewed) psychological, behavioral, and physically measured factors in these stratified groups were investigated. Among females, MetS was more common in the HQ-traits-group than in the LQ-traits-group (10.0% versus 7.5%,  
ISSN:1664-0640
1664-0640
DOI:10.3389/fpsyt.2023.1303840