Structure Characterization, Antioxidant and Immunomodulatory Activities of Polysaccharide from Pteridium aquilinum (L.) Kuhn

Pteridium aquilinum (L.) Kuhn (Pteridaceae family) has been widely used as a food and medicine in China and Korea. Previous studies indicate that P. aquilinum contains a variety of bioactive chemical components such as flavonoids, phenols, terpenoids, saponins, polysaccharides, and so on. In the pre...

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Published in:Foods 2022-06, Vol.11 (13), p.1834
Main Authors: Zhao, Zhe-Han, Ju, Xian-Yan, Wang, Kui-Wu, Chen, Xin-Juan, Sun, Hong-Xiang, Cheng, Ke-Jun
Format: Article
Language:English
Subjects:
antioxidant activity
Antioxidants
Arabinose
Chains
Chromatography
Ferns
Flavonoids
Food
Food industry
Food science
Free radicals
Fucose
Galactose
Immunomodulation
immunomodulatory activity
Mannose
Molecular weight
Phenols
Polysaccharides
Potassium
Pteridaceae
Pteridium aquilinum
Rhamnose
Saccharides
Saponins
Scavenging
Spectrum analysis
Structural analysis
structure characterization
Terpenes
Xylose
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Summary:Pteridium aquilinum (L.) Kuhn (Pteridaceae family) has been widely used as a food and medicine in China and Korea. Previous studies indicate that P. aquilinum contains a variety of bioactive chemical components such as flavonoids, phenols, terpenoids, saponins, polysaccharides, and so on. In the present study, a novel polysaccharide (named as PAP-3) with average molecular weight of 2.14 × 105 Da was obtained from P. aquilinum. The structure was studied through physicochemical and spectroscopic analysis. The results indicated that PAP-3 consists of arabinose, rhamnose, fucose, galactose, mannose, and xylose in a molar ratio of 1.58:1.00:3.26:4.57:4.81:3.33. The polysaccharide is mainly composed of (1→2)-linked xylose and (1→3,6)-linked mannose on the main chain, with (1→2)-linked xylose, (1→6)-linked mannose, and (1→6)- and (1→3,6)-linked galactose as side chains. Galactose, fucose, and xylose are located at the end of the side chains. The in vitro immunomodulatory and antioxidant activities were assayed. PAP-3 has strong free-radical scavenging activity on DPPH and ABTS radicals and significant immunomodulatory activity on RAW264.7 cells. These data provide useful information for further study on the polysaccharides of P. aquilinum and their applications in the food and medical industries.
ISSN:2304-8158
2304-8158
DOI:10.3390/foods11131834