First Case Report of Arrhythmogenic Right Ventricular Cardiomyopathy Showing Refractory Ventricular Tachycardia Induced by Thyroid Storm due to Graves’ Disease

A 48-year-old man who was diagnosed with arrhythmogenic right ventricular cardiomyopathy (ARVC) due to a plakophilin 2 gene mutation developed acute both-sided heart failure with rapid atrial fibrillation and was hospitalized. After admission, sustained ventricular tachycardia, which was refractory...

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Bibliographic Details
Published in:Case reports in endocrinology 2022-06, Vol.2022, p.1-8
Main Authors: Matsubara, Masaki, Tanaka, Tomohiro, Wakamiya, Akinori, Tamanaha, Tamiko, Makino, Hisashi, Tanei, Tomonori, Aiba, Takeshi, Kusano, Kengo, Hosoda, Kiminori
Format: Article
Language:English
Subjects:
Anti-arrhythmia drugs
Apixaban
Atrial fibrillation
Cardiac arrhythmia
Cardiomyocytes
Cardiomyopathy
Cardioversion
Care and treatment
Case Report
Case reports
Gene mutations
Genetic aspects
Graves disease
Health aspects
Heart
Heart diseases
Heart failure
Hyperthyroidism
Mutation
Thyroid diseases
Ventricular tachycardia
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Summary:A 48-year-old man who was diagnosed with arrhythmogenic right ventricular cardiomyopathy (ARVC) due to a plakophilin 2 gene mutation developed acute both-sided heart failure with rapid atrial fibrillation and was hospitalized. After admission, sustained ventricular tachycardia, which was refractory to antiarrhythmic agents, occurred repeatedly, and required electrical cardioversion. He was diagnosed with thyroid storm due to Graves’ disease, and treatment for hyperthyroidism was initiated. After the treatment, lethal arrhythmia did not reoccur, and biventricular heart failure ameliorated. To our best knowledge, this is the first report in English of a patient with ARVC showing refractory arrhythmia induced by thyroid storm due to Graves’ disease.
ISSN:2090-6501
2090-651X
DOI:10.1155/2022/6078148