Recent Advances in Separation and Analysis of Saponins in Natural Products

To better control the quality of saponins, ensure their biological activity and clinical therapeutic effect, and expand the development and application of saponins, this paper systematically and comprehensively reviews the separation and analytical methods of saponins in the past decade. Since 2010,...

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Bibliographic Details
Published in:Separations 2022-07, Vol.9 (7), p.163
Main Authors: Wang, Yi, Ma, Yan, Tao, Li, Zhang, Xiaoyan, Hao, Fusheng, Zhao, Shipeng, Han, Lu, Bai, Changcai
Format: Article
Language:English
Subjects:
Biological activity
Carbon
Chromatography
Efficiency
Herbal medicine
HPCCC
HPLC-MS
ionic liquid
Ionic liquids
Ions
Liquid chromatography
metabolomics
Methods
Natural products
QAMS
Qualitative analysis
Quality control
Researchers
saponin
Saponins
Scientific papers
Separation
Solvents
Sugar
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Summary:To better control the quality of saponins, ensure their biological activity and clinical therapeutic effect, and expand the development and application of saponins, this paper systematically and comprehensively reviews the separation and analytical methods of saponins in the past decade. Since 2010, the electronic databases of PubMed, Google Scholar, ISI Web of Science, Science Direct, Wiley, Springer, CNKI (National Knowledge Infrastructure, CNKI), Wanfang Med online, and other databases have been searched systematically. As a result, it is found that ionic liquids and high-performance countercurrent chromatography are the most popular extraction and separation techniques for saponins, and the combined chromatography technique is the most widely used method for the analysis of saponins. Liquid chromatography can be used in combination with different detectors to achieve qualitative or quantitative analysis and quality control of saponin compounds in medicinal materials and their preparations. This paper provides the latest valuable insights and references for the analytical methods and continued development and application of saponins.
ISSN:2297-8739
2297-8739
DOI:10.3390/separations9070163