Isolated systolic hypertension and insulin resistance assessment tools in young and middle-aged Chinese men with normal fasting glucose: a cross-sectional study

The vital role of insulin resistance (IR) in the pathogenesis of isolated systolic hypertension (ISH) has been expounded at the theoretical level. However, research on the correlation between some specific IR indicators and ISH is still rare, especially at different glycemic statuses. We conducted t...

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Bibliographic Details
Published in:Scientific reports 2022-01, Vol.12 (1), p.758-758, Article 758
Main Authors: Gu, Qing, Meng, Jian, Hu, Xue, Ge, Jun, Wang, Sui Jun, Liu, Xing Zhen
Format: Article
Language:English
Subjects:
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Adult
Age Factors
Asians
Biomarkers - blood
Blood Glucose - metabolism
Blood pressure
Cross-Sectional Studies
Fasting
Fasting - blood
Glucose
Homeostasis
Humanities and Social Sciences
Humans
Hypertension
Hypertension - diagnosis
Hypertension - etiology
Hypertension - therapy
Insulin
Insulin resistance
Insulin Resistance - physiology
Laboratory testing
Male
Middle age
Middle Aged
Models, Statistical
multidisciplinary
Science
Science (multidisciplinary)
Systole
Young Adult
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Summary:The vital role of insulin resistance (IR) in the pathogenesis of isolated systolic hypertension (ISH) has been expounded at the theoretical level. However, research on the correlation between some specific IR indicators and ISH is still rare, especially at different glycemic statuses. We conducted this study to explore the association between three IR indicators and ISH among young and middle-aged adults with normal fasting plasma glucose (NFG). This large cross-sectional study included 8246 young and middle-aged men with NFG and diastolic blood pressure 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-021-04763-x