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A need for tailored approach for patients with symptomatic intracranial atherosclerotic stenosis

Patients from the US were older, one-third had a prior stroke, one-fifth had coronary artery disease, 44% were on anti-platelet medication and 47% were on statin medication prior to admission. Patients with ICAS have a diverse spectrum of vascular phenotype, with variable degree of stenosis (presenc...

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Bibliographic Details
Published in:Annals of the Indian Academy of Neurology 2020-05, Vol.23 (3), p.253-254
Main Authors: Kate, Mahesh, Shuaib, Ashfaq
Format: Article
Language:English
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Summary:Patients from the US were older, one-third had a prior stroke, one-fifth had coronary artery disease, 44% were on anti-platelet medication and 47% were on statin medication prior to admission. Patients with ICAS have a diverse spectrum of vascular phenotype, with variable degree of stenosis (presence of sub-clinical perfusion deficits), focal and diffuse atherosclerosis pattern, collateral artery distribution and plaque enhancement suggestive of inflammation, hemorrhage and vascularity. [7] RIC has been tested in a phase 2 study in patients with ICAS and shown to reduce the annual incidence of recurrent stroke and improvement in cerebral blood flow.
ISSN:0972-2327
1998-3549
DOI:10.4103/aian.AIAN_623_19