Dyslipidaemia associated with the highly active antiretroviral therapy in AIDS patient: reversion after switching (stavudine to tenofovir and lopinavir/ritonavir to atazanavir/ritonavir)

Antiretroviral therapy has been associated with hyperlipidemia in AIDS patients. This case illustrates the classic metabolic effects associated to the HAART including protease inhibitors and/or stavudine. It was showed that the management of the HAART-associated dyslipidaemia with conventional antih...

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Bibliographic Details
Published in:The Brazilian journal of infectious diseases 2007-04, Vol.11 (2), p.290-292
Main Authors: Domingos, Hamilton, da Cunha, Rivaldo Venâncio, Paniago, Anamaria Mello Miranda
Format: Article
Language:English
Subjects:
Adult
AIDS
Anti-HIV Agents - administration & dosage
Anti-HIV Agents - adverse effects
Antiretroviral Therapy, Highly Active - adverse effects
dyslipidaemia
Dyslipidemias - chemically induced
Dyslipidemias - drug therapy
HIV Infections - blood
HIV Infections - drug therapy
HIV Protease Inhibitors - administration & dosage
HIV Protease Inhibitors - adverse effects
Humans
Hypolipidemic Agents - therapeutic use
INFECTIOUS DISEASES
Lipids - blood
Male
switching strategy
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Description
Summary:Antiretroviral therapy has been associated with hyperlipidemia in AIDS patients. This case illustrates the classic metabolic effects associated to the HAART including protease inhibitors and/or stavudine. It was showed that the management of the HAART-associated dyslipidaemia with conventional antihyperlipidemic therapy may fail, being the switching strategy the best option.
ISSN:1413-8670
1678-4391
DOI:10.1590/S1413-86702007000200025