Generation of a control iPS cell line (JUCGRMi005-A) with no abnormalities in Parkinson's disease-related genes

Appropriate control induced pluripotent stem cells (iPSCs) are essential for studying iPSCs derived from patients with Parkinson’s disease (PD). In this study, we established an iPSC line from a healthy male donor. The iPSCs showed pluripotency, capacity to differentiate into three germ layers, and...

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Bibliographic Details
Published in:Stem cell research 2024-02, Vol.74, p.103271-103271, Article 103271
Main Authors: Ishikawa, Kei-ichi, Shiga, Takahiro, Funayama, Manabu, Hattori, Nobutaka, Akamatsu, Wado
Format: Article
Language:English
Subjects:
Cell Line
Humans
Induced Pluripotent Stem Cells - metabolism
Male
Parkinson Disease - genetics
Parkinson Disease - metabolism
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Summary:Appropriate control induced pluripotent stem cells (iPSCs) are essential for studying iPSCs derived from patients with Parkinson’s disease (PD). In this study, we established an iPSC line from a healthy male donor. The iPSCs showed pluripotency, capacity to differentiate into three germ layers, and normal karyotypes. Additionally, we confirmed that the iPSC line did not exhibit any PD-related gene abnormalities. This iPSC line will be useful for PD research.
ISSN:1873-5061
1876-7753
DOI:10.1016/j.scr.2023.103271