Allergic rhinitis, asthma and laryngopharyngeal reflux disease: a cross-sectional study on their reciprocal relations

Allergic rhinitis (AR) is a common medical condition worldwide. It is an inflammation in the nasal mucosa due to allergen exposure throughout the year. Laryngopharyngeal reflux (LPR) is another medical condition that can overlap with AR. LPR can be considered an extra oesophageal manifestation of ga...

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Bibliographic Details
Published in:Scientific reports 2021-02, Vol.11 (1), p.2870-2870, Article 2870
Main Authors: Kakaje, Ameer, Alhalabi, Mohammad Marwan, Alyousbashi, Ayham, Ghareeb, Ayham
Format: Article
Language:English
Subjects:
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692/308
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Adolescent
Adult
Allergens
Allergic rhinitis
Asthma
Asthma - complications
Asthma - diagnosis
Asthma - epidemiology
Asthma - immunology
Cross-Sectional Studies
Esophagus
Female
Gastroesophageal reflux
Humanities and Social Sciences
Humans
Laryngopharyngeal Reflux - complications
Laryngopharyngeal Reflux - diagnosis
Laryngopharyngeal Reflux - epidemiology
Laryngopharyngeal Reflux - immunology
Male
Mucosa
multidisciplinary
Quality of Life
Respiratory System - immunology
Rhinitis
Rhinitis, Allergic - complications
Rhinitis, Allergic - diagnosis
Rhinitis, Allergic - epidemiology
Rhinitis, Allergic - immunology
Risk Factors
Science
Science (multidisciplinary)
Self Report - statistics & numerical data
Severity of Illness Index
Syria - epidemiology
Young Adult
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Summary:Allergic rhinitis (AR) is a common medical condition worldwide. It is an inflammation in the nasal mucosa due to allergen exposure throughout the year. Laryngopharyngeal reflux (LPR) is another medical condition that can overlap with AR. LPR can be considered an extra oesophageal manifestation of gastro-oesophageal reflux disease (GORD) or a different entity. Its diagnosis imposes a real challenge as it has a wide range of unspecific symptoms. Although AR and LPR are not life-threatening, they can severely affect the quality of life for years and cause substantial distress. Moreover, having AR is associated with having asthma which is also in turn associated with GORD. This is a cross-sectional study which used surveys distributed online on Social Media and targeted people across Syria. All participants who responded to the key questions were included. Reflux symptom index (RSI) was used for LPR, and score for allergic rhinitis (SFAR) was used for AR. Demographic questions and whether the participant had asthma were also included in the survey. We found that there was an association between the symptoms of LPR and AR p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-80793-1