Seasonal adherence to, and effectiveness of, subcutaneous interferon β-1a administered by RebiSmart® in patients with relapsing multiple sclerosis: results of the 1-year, observational GEPAT-SMART study

Little is known about whether tolerability and adherence to treatment can be influenced by weather and temperature conditions. The objective of this study was to assess monthly and seasonal adherence to and safety of sc IFN-β1a (Rebif®, Merck) in relapsing-remitting multiple sclerosis (RRMS) patient...

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Bibliographic Details
Published in:BMC neurology 2018-11, Vol.18 (1), p.186-186, Article 186
Main Authors: Deftereos, Spyros N, Koutlas, Evangelos, Koutsouraki, Efrosini, Kyritsis, Athanassios, Papathanassopoulos, Panagiotis, Fakas, Nikolaos, Tsimourtou, Vaia, Vlaikidis, Nikolaos, Tavernarakis, Antonios, Voumvourakis, Konstantinos, Arvanitis, Michalis, Sakellariou, Dimitrios, DeLorenzo, Filippo
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Clinical efficacy
Clinical trials
Disabled Persons
Disease Progression
Enrollments
Epidemiology
Ethics
Female
Greece
Humans
Interferon
Interferon beta-1a - therapeutic use
Interferons
Male
Middle Aged
Multiple sclerosis
Multiple Sclerosis, Relapsing-Remitting - drug therapy
Patient compliance
Patients
Prospective Studies
Rebif
Rebismart
Registration
Seasonal variations
Seasons
Studies
Substance abuse treatment
Treatment adherence and compliance
Weather
Young Adult
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Summary:Little is known about whether tolerability and adherence to treatment can be influenced by weather and temperature conditions. The objective of this study was to assess monthly and seasonal adherence to and safety of sc IFN-β1a (Rebif®, Merck) in relapsing-remitting multiple sclerosis (RRMS) patients using the RebiSmart® electronic autoinjector. A multicentre, prospective observational study in Greece in adult RRMS patients with EDSS
ISSN:1471-2377
1471-2377
DOI:10.1186/s12883-018-1179-0