Uterine involvement in epithelial ovarian cancer and its risk factors

• Published in: Journal of ovarian research 2021-12, Vol.14 (1), p.171-171, Article 171
• Main Authors: Zamani, Narges, Mousavi, Azam Sadat, Akhavan, Setare, Sheikhhasani, Shahrzad, Nikfar, Somayeh, Feizabad, Elham, Rezayof, Elahe, Modares Gilani, Mitra
• Format: Article
• Language: English
• Subjects: Adult; Age; Aged; Aged, 80 and over; Biopsy; Cancer; Carboplatin; Carcinoma; Carcinoma, Ovarian Epithelial - pathology; Chemotherapy; Endometrial cancer; Endometrial eeoplasms; Endometrium; Female; Health aspects; Histology; Humans; Hyperplasia; Hysterectomy; Medical prognosis; Metastases; Metastasis; Middle Aged; Neoplasm Grading; Neoplasm Staging; Oncology, Experimental; Ovarian cancer; Ovarian epithelial; Ovarian Neoplasms - pathology; Pathology; Patients; Retrospective Studies; Risk eactor; Risk Factors; Risk groups; Surgery; Tumors; Uterine cancer; Uterus - pathology; Women; Womens health
• ISSN: 1757-2215; 1757-2215
• DOI: 10.1186/s13048-021-00925-7

Epithelial ovarian cancer (EOC) is an extremely aggressive and lethal carcinoma. Specific data that identify high-risk groups with uterine involvement are not available. Thus, this study aimed to evaluate a gross number of women with EOC to obtain the frequency of uterine involvement and its risk factors. This retrospective observational study was conducted on 1900 histologically confirmed EOC women, diagnosed and treated in our tertiary hospital from March 2009 to September 2020. Data including their demographic, medical and pathological findings were collected. From 1900 histologically confirmed EOC women, 347 patients were eligible for participations. The mean age of study patients was 51.31 ± 11.37 years with the age range of 25 to 87 years. Uterine involvement was detected in 49.6% (173) of the patients either macroscopic (47.4%) or microscopic (52.6%) types. Uterine involvement was significantly associated with having AUB (P-value = 0.002), histological type of ovary tumor (P-value