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Resting Heart Rate and Associations With Clinical Measures From the Project Baseline Health Study: Observational Study

Though widely used, resting heart rate (RHR), as measured by a wearable device, has not been previously evaluated in a large cohort against a variety of important baseline characteristics. This study aimed to assess the validity of the RHR measured by a wearable device compared against the gold stan...

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Published in:Journal of medical Internet research 2024-12, Vol.26 (3), p.e60493
Main Authors: Feng, Kent Y, Short, Sarah A, Saeb, Sohrab, Carroll, Megan K, Olivier, Christoph B, Simard, Edgar P, Swope, Susan, Williams, Donna, Eckstrand, Julie, Pagidipati, Neha, Shah, Svati H, Hernandez, Adrian F, Mahaffey, Kenneth W
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Language:English
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Summary:Though widely used, resting heart rate (RHR), as measured by a wearable device, has not been previously evaluated in a large cohort against a variety of important baseline characteristics. This study aimed to assess the validity of the RHR measured by a wearable device compared against the gold standard of ECG (electrocardiography), and assess the relationships between device-measured RHR and a broad range of clinical characteristics. The Project Baseline Health Study (PHBS) captured detailed demographic, occupational, social, lifestyle, and clinical data to generate a deeply phenotyped cohort. We selected an analysis cohort within it, which included participants who had RHR determined by both ECG and the Verily Study Watch (VSW). We examined the correlation between these simultaneous RHR measures and assessed the relationship between VSW RHR and a range of baseline characteristics, including demographic, clinical, laboratory, and functional assessments. From the overall PBHS cohort (N=2502), 875 (35%) participants entered the analysis cohort (mean age 50.9, SD 16.5 years; n=519, 59% female and n=356, 41% male). The mean and SD of VSW RHR was 66.6 (SD 11.2) beats per minute (bpm) for female participants and 64.4 (SD 12.3) bpm for male participants. There was excellent reliability between the two measures of RHR (ECG and VSW) with an intraclass correlation coefficient of 0.946. On univariate analyses, female and male participants had similar baseline characteristics that trended with higher VSW RHR: lack of health care insurance (both P
ISSN:1438-8871
1439-4456
1438-8871
DOI:10.2196/60493