Application of the ATLAS score for evaluating the severity of Clostridium difficile infection in teaching hospitals in Mexico

For clinicians, a practical bedside tool for severity assessment and prognosis of patients with Clostridium difficile infection is a highly desirable unmet medical need. Two general teaching hospitals in northeast Mexico. Adult patients with C. difficile infection. Prospective observational study. P...

Full description

Saved in:
Bibliographic Details
Published in:The Brazilian journal of infectious diseases 2015-07, Vol.19 (4), p.399-402
Main Authors: Hernández-García, Raúl, Garza-González, Elvira, Miller, Mark, Arteaga-Muller, Giovanna, Galván-de los Santos, Alejandra María, Camacho-Ortiz, Adrián
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Care and treatment
Clostridium difficile
Clostridium infections
Clostridium Infections - classification
Clostridium Infections - diagnosis
Clostridium Infections - mortality
Cross infection
Diagnosis
Female
Health aspects
Hospitals, Teaching
Humans
INFECTIOUS DISEASES
Length of Stay
Male
Mexico
Middle Aged
Mortality
Original
Prediction rule
Prognosis
Prospective Studies
Severity of Illness Index
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:For clinicians, a practical bedside tool for severity assessment and prognosis of patients with Clostridium difficile infection is a highly desirable unmet medical need. Two general teaching hospitals in northeast Mexico. Adult patients with C. difficile infection. Prospective observational study. Patients included had a median of 48 years of age, 54% of male gender and an average of 24.3 days length of hospital stay. Third generation cephalosporins were the antibiotics most commonly used prior to C. difficile infection diagnosis. Patients diagnosed with C. difficile infection had a median ATLAS score of 4 and 56.7% of the subjects had a score between 4 and 7 points. Patients with a score of 8 through 10 points had 100% mortality. The ATLAS score is a potentially useful tool for the routine evaluation of patients at the time of C. difficile infection diagnosis. At 30 days post-diagnosis, patients with a score of ≤3 points had 100% survival while all of those with scores ≥8 died. Patients with scores between 4 and 7 points had a greater probability of colectomy with an overall cure rate of 70.1%.
ISSN:1413-8670
1678-4391
1678-4391
DOI:10.1016/j.bjid.2015.05.005