The Relationship between Generalized and Abdominal Obesity with Diabetic Kidney Disease in Type 2 Diabetes: A Multiethnic Asian Study and Meta-Analysis

This study examined the associations of body mass index (BMI), waist circumference (WC), waist-hip ratio (WHR) and waist-height ratio (WHtR) with diabetic kidney disease (DKD) in a clinical sample of Asian patients with type 2 diabetes (T2DM); substantiated with a meta-analysis of the above associat...

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Published in:Nutrients 2018-11, Vol.10 (11), p.1685
Main Authors: Man, Ryan Eyn Kidd, Gan, Alfred Tau Liang, Fenwick, Eva Katie, Gupta, Preeti, Wong, Mark Yu Zheng, Wong, Tien Yin, Tan, Gavin Siew Wei, Teo, Boon Wee, Sabanayagam, Charumathi, Lamoureux, Ecosse Luc
Format: Article
Language:English
Subjects:
Aged
Asian Continental Ancestry Group
Body Mass Index
Diabetes Mellitus, Type 2 - epidemiology
diabetic kidney disease
Diabetic Nephropathies - epidemiology
Ethnic Groups
Female
Humans
Male
meta-analysis
Middle Aged
obesity
Obesity, Abdominal - epidemiology
Risk Factors
Singapore
Waist Circumference
Waist-Height Ratio
Waist-Hip Ratio
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Summary:This study examined the associations of body mass index (BMI), waist circumference (WC), waist-hip ratio (WHR) and waist-height ratio (WHtR) with diabetic kidney disease (DKD) in a clinical sample of Asian patients with type 2 diabetes (T2DM); substantiated with a meta-analysis of the above associations. We recruited 405 patients with T2DM (mean (standard deviation (SD)) age: 58 (7.5) years; 277 (68.4%) male; 203 (50.1%) with DKD) from a tertiary care centre in Singapore. DKD was defined as urinary albumin-creatinine ratio >3.3 mg/mmoL and/or estimated glomerular filtration rate
ISSN:2072-6643
2072-6643
DOI:10.3390/nu10111685