Study protocol of the Edinburgh and Lothian Virus Intervention Study in Kids: a randomised controlled trial of hypertonic saline nose drops in children with upper respiratory tract infections (ELVIS Kids)

IntroductionEdinburgh and Lothians’ Viral Intervention Study Kids is a parallel, open-label, randomised controlled trial of hypertonic saline (HS) nose drops (~2.6% sodium chloride) vs standard care in children

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Bibliographic Details
Published in:BMJ open 2021-05, Vol.11 (5), p.e049964-e049964
Main Authors: Ramalingam, Sandeep, Graham, Catriona, Oatey, Katherine, Rayson, Phillip, Stoddart, Andrew, Sheikh, Aziz, Cunningham, Steve, Abernathy, Brittney, Baggot, Julie, Buchan, Ruaridh, Black, Gillian, Frampton, Louise, Matos, Naomi, McGivern, Elinore, McKernan, Rachel, Miller, Debbie, Millar, Margaret, Mortimer, Sheila, Paterson, Finny, Ramsay, Maxine, Thomson, Joan, Ward, Emma, Waters, Jacqueline
Format: Article
Language:English
Subjects:
Administration, Intranasal
Bacterial infections
Cervical cancer
Child
Children & youth
Childrens health
community child health
COVID-19
Diaries
Households
Humans
Illnesses
Infections
Intervention
Laboratories
neonatology
Nose
paediatric infectious disease & immunisation
Paediatrics
Parents & parenting
Pediatrics
Primary care
Randomized Controlled Trials as Topic
Respiratory diseases
Respiratory Tract Infections - drug therapy
Saline Solution
SARS-CoV-2
Scotland
Sodium Chloride - therapeutic use
State Medicine
Viral infections
virology
Viruses
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Description
Summary:IntroductionEdinburgh and Lothians’ Viral Intervention Study Kids is a parallel, open-label, randomised controlled trial of hypertonic saline (HS) nose drops (~2.6% sodium chloride) vs standard care in children
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2021-049964