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Cardiac sarcoidosis completely mimicking biventricular arrhythmogenic cardiomyopathy
Cardiac sarcoidosis (CS) is a chameleon of cardiology, and it can mimic different cardiac diseases; among them is arrhythmogenic cardiomyopathy (ACM). We admitted a 70‐year‐old female patient with heart failure symptoms in 2015, who fulfilled all major ECG and non‐invasive imaging criteria of bivent...
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Published in: | ESC Heart Failure 2022-12, Vol.9 (6), p.4304-4314 |
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description | Cardiac sarcoidosis (CS) is a chameleon of cardiology, and it can mimic different cardiac diseases; among them is arrhythmogenic cardiomyopathy (ACM). We admitted a 70‐year‐old female patient with heart failure symptoms in 2015, who fulfilled all major ECG and non‐invasive imaging criteria of biventricular ACM. She was well with the recommended medications for 3 years, showing only isolated cardiac involvement, but in 2018, cervical and mediastinal lymphadenopathy appeared and cervical lymph node core biopsy histology, bronchoalveolar lavage flow cytometry strongly suggested extracardiac sarcoidosis. Therefore, our suspicion was that sarcoidosis is responsible for the cardiac involvement, which was not confirmed by PET‐CT and gallium scintigraphy examinations. At the end of 2018, she died in septicaemia with multiorgan failure, and only autopsy verified her CS. A new ECG algorithm published in 2021 for the differential diagnosis of CS and biventricular ACM, when applied on her ECGs recorded in 2015, suggested the diagnosis of CS. |
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We admitted a 70‐year‐old female patient with heart failure symptoms in 2015, who fulfilled all major ECG and non‐invasive imaging criteria of biventricular ACM. She was well with the recommended medications for 3 years, showing only isolated cardiac involvement, but in 2018, cervical and mediastinal lymphadenopathy appeared and cervical lymph node core biopsy histology, bronchoalveolar lavage flow cytometry strongly suggested extracardiac sarcoidosis. Therefore, our suspicion was that sarcoidosis is responsible for the cardiac involvement, which was not confirmed by PET‐CT and gallium scintigraphy examinations. At the end of 2018, she died in septicaemia with multiorgan failure, and only autopsy verified her CS. A new ECG algorithm published in 2021 for the differential diagnosis of CS and biventricular ACM, when applied on her ECGs recorded in 2015, suggested the diagnosis of CS.</description><identifier>ISSN: 2055-5822</identifier><identifier>EISSN: 2055-5822</identifier><identifier>DOI: 10.1002/ehf2.14123</identifier><identifier>PMID: 36045019</identifier><language>eng</language><publisher>England: John Wiley & Sons, Inc</publisher><subject>Aged ; Akinesia ; Aneurysms ; arrhythmogenic cardiomyopathy ; Cardiac arrhythmia ; Cardiology ; Cardiomyopathies - diagnosis ; Cardiomyopathy ; Dyskinesia ; Edema ; Electrocardiography ; Female ; Heart ; heart failure ; Humans ; Magnetic resonance imaging ; Medical imaging ; Morphology ; Myocarditis ; Positron Emission Tomography Computed Tomography ; Pulmonary arteries ; Sarcoidosis ; Sarcoidosis - diagnosis ; Sinuses ; Task forces</subject><ispartof>ESC Heart Failure, 2022-12, Vol.9 (6), p.4304-4314</ispartof><rights>2022 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.</rights><rights>2022. This work is published under http://creativecommons.org/licenses/by-nc/4.0/ (the “License”). 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We admitted a 70‐year‐old female patient with heart failure symptoms in 2015, who fulfilled all major ECG and non‐invasive imaging criteria of biventricular ACM. She was well with the recommended medications for 3 years, showing only isolated cardiac involvement, but in 2018, cervical and mediastinal lymphadenopathy appeared and cervical lymph node core biopsy histology, bronchoalveolar lavage flow cytometry strongly suggested extracardiac sarcoidosis. Therefore, our suspicion was that sarcoidosis is responsible for the cardiac involvement, which was not confirmed by PET‐CT and gallium scintigraphy examinations. At the end of 2018, she died in septicaemia with multiorgan failure, and only autopsy verified her CS. A new ECG algorithm published in 2021 for the differential diagnosis of CS and biventricular ACM, when applied on her ECGs recorded in 2015, suggested the diagnosis of CS.</description><subject>Aged</subject><subject>Akinesia</subject><subject>Aneurysms</subject><subject>arrhythmogenic cardiomyopathy</subject><subject>Cardiac arrhythmia</subject><subject>Cardiology</subject><subject>Cardiomyopathies - diagnosis</subject><subject>Cardiomyopathy</subject><subject>Dyskinesia</subject><subject>Edema</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Heart</subject><subject>heart failure</subject><subject>Humans</subject><subject>Magnetic resonance imaging</subject><subject>Medical imaging</subject><subject>Morphology</subject><subject>Myocarditis</subject><subject>Positron Emission Tomography Computed Tomography</subject><subject>Pulmonary arteries</subject><subject>Sarcoidosis</subject><subject>Sarcoidosis - diagnosis</subject><subject>Sinuses</subject><subject>Task forces</subject><issn>2055-5822</issn><issn>2055-5822</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNp9kU1r20AQhpeS0pg0l_6AIuit4GT2U9KxGOcDArm452X2Q_a6ktfdlVv07yNbrukppxmGh2eGeQn5QuGOArB7v2nYHRWU8Q9kxkDKuawYu_qvvya3OW8BgEpFJROfyDVXICTQekZWC0wuoC0yJhuDiznkwsZu3_ret0PRhS7YX2G3Lkz443d9CvbQYiowpc3Qb7q49rtgC3u0xG6Ie-w3w2fyscE2-9tzvSE_H5arxdP85fXxefHjZW5Fzfm8KlXlOEqFKB13YLis0HJ0plbY2PFC4KaqgDIlwNbGU-upqCw0YJgqBb8hz5PXRdzqfQodpkFHDPo0iGmtMfXBtl7L0U0pr8q6MQKNQnCqdMI5h8zS0o-ub5Nrn-Lvg8-93sZD2o3na1ZKpWgpSxip7xNlU8w5-eaylYI-5qGPeehTHiP89aw8mM67C_rv-yNAJ-BvaP3wjkovnx7YJH0Ds_GVBA</recordid><startdate>202212</startdate><enddate>202212</enddate><creator>Vereckei, András</creator><creator>Katona, Gábor</creator><creator>Révész, Katalin</creator><creator>Vágó, Hajnalka</creator><creator>Müller, Veronika</creator><creator>Nagy, Beáta</creator><creator>Nagy, Péter</creator><creator>Sepp, Róbert</creator><creator>Suvarna, Kim</creator><general>John Wiley & Sons, Inc</general><general>Wiley</general><scope>24P</scope><scope>WIN</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>DOA</scope></search><sort><creationdate>202212</creationdate><title>Cardiac sarcoidosis completely mimicking biventricular arrhythmogenic cardiomyopathy</title><author>Vereckei, András ; 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among them is arrhythmogenic cardiomyopathy (ACM). We admitted a 70‐year‐old female patient with heart failure symptoms in 2015, who fulfilled all major ECG and non‐invasive imaging criteria of biventricular ACM. She was well with the recommended medications for 3 years, showing only isolated cardiac involvement, but in 2018, cervical and mediastinal lymphadenopathy appeared and cervical lymph node core biopsy histology, bronchoalveolar lavage flow cytometry strongly suggested extracardiac sarcoidosis. Therefore, our suspicion was that sarcoidosis is responsible for the cardiac involvement, which was not confirmed by PET‐CT and gallium scintigraphy examinations. At the end of 2018, she died in septicaemia with multiorgan failure, and only autopsy verified her CS. A new ECG algorithm published in 2021 for the differential diagnosis of CS and biventricular ACM, when applied on her ECGs recorded in 2015, suggested the diagnosis of CS.</abstract><cop>England</cop><pub>John Wiley & Sons, Inc</pub><pmid>36045019</pmid><doi>10.1002/ehf2.14123</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aged Akinesia Aneurysms arrhythmogenic cardiomyopathy Cardiac arrhythmia Cardiology Cardiomyopathies - diagnosis Cardiomyopathy Dyskinesia Edema Electrocardiography Female Heart heart failure Humans Magnetic resonance imaging Medical imaging Morphology Myocarditis Positron Emission Tomography Computed Tomography Pulmonary arteries Sarcoidosis Sarcoidosis - diagnosis Sinuses Task forces |
title | Cardiac sarcoidosis completely mimicking biventricular arrhythmogenic cardiomyopathy |
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