Frequncy and etiology of lymphadenopathy in Iranian HIV/AIDS patients

To estimate and outline the frequency and etiology of lymphadenopathy in HIV/AIDS patients. This study was conducted on 178 consecutive HIV/AIDS patient files for etiologies (categorized into three sub-groups: definite, probable and possible) and associated factors of local and generalized lymphaden...

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Bibliographic Details
Published in:Asian Pacific journal of tropical biomedicine 2014-05, Vol.4 (Suppl 1), p.S171-S176
Main Authors: Hadadi, Azar, Jafari, Sirous, Jebeli, Zahra Hoseini, Hamidian, Reza
Format: Article
Language:English
Subjects:
AIDS
Clinical Research
Etiology
HIV
Human immunodeficiency virus
intravenous injection
Lymphadenopathy
lymphoma
males
patients
physicians
tuberculosis
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Summary:To estimate and outline the frequency and etiology of lymphadenopathy in HIV/AIDS patients. This study was conducted on 178 consecutive HIV/AIDS patient files for etiologies (categorized into three sub-groups: definite, probable and possible) and associated factors of local and generalized lymphadenopathy. Seventy-two (40.45%) patients including 63 male patients (87.5%) developed lymphadenopathy. HIV in lymphadenopathy(+) patients was most commonly transmitted intravenously (n=49). Generalized and localized lymphadenopathy respectively occurred in 27 (37.50%) and 45 (62.50%) patients, mainly in the cervical region (28.9% for local and 63% for generalized lymphadenopathy). The most common causes of lymphadenopathy were tuberculosis (n=24, 33.3%) and lymphoma (n=12, 16.6%). The frequency of lymphadenopathy was non-significantly higher in patients with AIDS (CD4 count 200 cell/µL). Lymphadenopathy in HIV/AIDS patients may reflect a serious condition, most likely tuberculosis and lymphoma. Since patients might underestimate lymphadenopathy, physicians would rather list these entities for diagnosis.
ISSN:2221-1691
2588-9222
DOI:10.12980/APJTB.4.2014C1253