Basaloid follicular hamartoma associated with follicular mucinosis and inflammation

Basaloid follicular hamartoma is a benign, superficial malformation of hair follicles that can be mistaken both clinical and histopathologically for basal cell carcinoma. Basaloid follicular hamartoma has been linked to a mutation in the PTCH-1 gene, which is part of the same pathway involved in Gor...

Full description

Saved in:
Bibliographic Details
Published in:Anais brasileiros de dermatología 2022-01, Vol.97 (1), p.45-48
Main Authors: Edelman, Solange, Torres Huamani, Adriana Natalia, Centeno, María Del Valle, Cervini, Andrea Bettina
Format: Article
Language:English
Subjects:
basal cell
Carcinoma
Carcinoma, Basal Cell
Case Report
Child
DERMATOLOGY
Genes
Genes, tumor suppressor
Hamartoma
Hamartoma - complications
Humans
Inflammation
Mucinosis, Follicular
Skin Neoplasms
tumor suppressor
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Basaloid follicular hamartoma is a benign, superficial malformation of hair follicles that can be mistaken both clinical and histopathologically for basal cell carcinoma. Basaloid follicular hamartoma has been linked to a mutation in the PTCH-1 gene, which is part of the same pathway involved in Gorlin-Goltz syndrome. Here we present a 9-year-old patient with an asymptomatic congenital lesion on the forehead, which increased in size over the years. Histopathology showed a basaloid follicular hamartoma associated with follicular mucinosis and inflammation. Gorlin-Goltz syndrome was ruled out by clinical examination.
ISSN:0365-0596
1806-4841
1806-4841
DOI:10.1016/j.abd.2020.10.012