Fungal infections in immunocompromised critically ill patients

Diverse pathogenic fungi can produce severe infections in immunocompromised patients, thereby justifying intensive care unit (ICU) admissions. In some cases, the infections can develop in immunocompromised patients who were previously admitted to the ICU. Aspergillus spp., Pneumocystis jirovecii, Ca...

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Bibliographic Details
Published in:Journal of intensive medicine 2024-07, Vol.4 (3), p.299-306
Main Authors: Garnacho-Montero, José, Barrero-García, Irene, León-Moya, Cristina
Format: Article
Language:English
Subjects:
Antifungal
Critically ill patient
Immunocompromised patient
Invasive aspergillosis
Invasive candidiasis
Pneumocystis jirovecii
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Summary:Diverse pathogenic fungi can produce severe infections in immunocompromised patients, thereby justifying intensive care unit (ICU) admissions. In some cases, the infections can develop in immunocompromised patients who were previously admitted to the ICU. Aspergillus spp., Pneumocystis jirovecii, Candida spp., and Mucorales are the fungi that are most frequently involved in these infections. Diagnosis continues to be challenging because symptoms and signs are unspecific. Herein, we provide an in-depth review about the diagnosis, with emphasis on recent advances, and treatment of these invasive fungal infections in the ICU setting.
ISSN:2667-100X
2667-100X
DOI:10.1016/j.jointm.2024.01.005