The association between the change in severity score from baseline and the outcomes of critically ill patients was enhanced by integration of bioimpedance analysis parameters

• Published in: Scientific reports 2024-06, Vol.14 (1), p.14681-8, Article 14681
• Main Authors: Hu, Zhen, Li, Chuan, Zhu, Shuhua, Ge, Yongchun, Gong, Dehua
• Format: Article
• Language: English
• Subjects: 692/308; 692/308/409; Adult; Aged; Bioimpedance analysis; Critical Illness - mortality; Dynamic change; Electric Impedance; Female; Humanities and Social Sciences; Humans; Intensive care; Intensive Care Units; Male; Middle Aged; Mortality; multidisciplinary; Outcomes; Patients; Phase angle; Prognosis; Regression analysis; Science; Science (multidisciplinary); Severity of Illness Index; Severity scores; Simplified Acute Physiology Score
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-024-65782-y

The study of the outcomes of critically ill patients has been a hard stuff in the field of intensive care. To explore the relationship between changes of severity scores, bioelectrical impedance analysis (BIA) and outcomes of critically ill patients, we enrolled patients (n = 206) admitted to intensive care unit (ICU) in Jinling Hospital from 2018 to 2021 with records of BIA on the days 1- and 3- ICU. Collected BIA and clinical data including simplified acute physiology score II (SAPS II) and sequential organ failure assessment. According to the baseline and change of severity scores or phase angle (PA) values, the patients were divided into: G–G, baseline good status, 3rd day unchanged; G–B, baseline good status, 3rd day deteriorated; B–G, baseline bad status, 3rd day improved; and B–B, baseline bad status, 3rd day unchanged. According to PA, the mortality of group G–G was 8.6%, and it was greater than 50% in group B–B for severity scores. The new score combining PA and severity scores established. Multivariate logistic regression analysis revealed that PA–SAPS II score was the only independent factor for 90-day mortality ( P