Favorable factors for the survival of ST-segment elevation myocardial infarction patients with medium- and high-risk thrombolysis in myocardial infarction scores

• Published in: BMC cardiovascular disorders 2023-12, Vol.23 (1), p.614-614, Article 614
• Main Authors: Luo, Zhengli, Feng, Yuan, Luo, Dan, Li, Shiyang, Xiao, Kaiyi, Shen, Hongmei, Hu, Qiang
• Format: Article
• Language: English
• Subjects: Angina pectoris; Blood clot; Blood coagulation; Blood platelets; Blood pressure; Cardiovascular disease; Coronary vessels; Development and progression; Diagnosis; Electrocardiography; Emergency percutaneous coronary intervention; Favorable factors; Heart attack; Heart attacks; Heart rate; Hemoglobin; High density lipoprotein; Hospitals; In-hospital survival; Lipoproteins; Lymphocytes; Medical prognosis; Mortality; Myocardial infarction; Neutrophils; Normal distribution; Receiver operating characteristics curve; Risk groups; Software; ST-segment myocardial infarction; Statistical analysis; Thrombolysis; Thrombolysis in myocardial infarction score; Thrombosis; Variance analysis
• ISSN: 1471-2261; 1471-2261
• DOI: 10.1186/s12872-023-03628-7

ST-segment myocardial infarction (STEMI) is a time-sensitive emergency. This study screened the favorable factors for the survival of STEMI patients with medium- and high-risk thrombolysis in myocardial infarction (TIMI) scores. According to the TIMI scores at admission, 433 STEMI patients were retrospectively and consecutively selected and allocated into low-/medium-/high-risk groups, with their general information/blood routine/biochemical indicators/coagulation indicators documented. The factors influencing the in-hospital survival of STEMI patients were analyzed using univariate and multivariate logistic regression analyses. Moreover, the predictive value of favorable factors was analyzed by receiver operating characteristics (ROC) curve, and patients were assigned into high/low level groups based on the cut-off value of these factors, with their in-hospital survival rates compared. The in-hospital survival rate of the medium-/high-risk groups was lower than that of the low-risk group. Emergency percutaneous coronary intervention (PCI), lymphocyte (LYM), total protein (TP), albumin (ALB), and sodium (Na) were independent favorable factors for in-hospital survival in the medium-/high-risk groups. Besides, LYM > 1.275 × 10 /L, TP > 60.25 g/L, ALB > 34.55 g/L, and Na > 137.9 mmo1/L had auxiliary predictive value for the survival of STEMI patients with medium-/high-risk TIMI scores. Patients with high levels of LYM, TP, ALB, and Na exhibited higher in-hospital survival rates than patients with low levels. For STEMI patients with medium- and high-risk TIMI scores, accepting emergency PCI and normal levels of LYM, TP, ALB, and Na were more conducive to in-hospital survival.