Contrast-enhanced ultrasonography combined with superb microvascular imaging for preoperative diagnosis of sporadic intra-abdominal desmoid-type fibromatosis: A case report

• Published in: Radiology case reports 2024-09, Vol.19 (9), p.3988-3993
• Main Authors: Komi, Kazuhiro, Fujita, Minoru, Manabe, Noriaki, Takaoka, Munenori, Kato, Katsuya, Fujiwara, Hideyo, Konishi, Takako, Bukeo, Emiko, Misawa, Hiraku, Nakamura, Jun, Ayaki, Maki, Murao, Takahisa, Suehiro, Mitsuhiko, Akiyama, Takashi, Kawamoto, Hirofumi, Kamada, Tomoari, Urakami, Atsushi, Naomoto, Yoshio, Yamatsuji, Tomoki, Moriya, Takuya, Haruma, Ken, Hata, Jiro
• Format: Article
• Language: English
• Subjects: Case Report; Contrast-enhanced ultrasonography; Diagnosis; Intra-abdominal desmoid-type fibromatosis; Superb microvascular imaging; Transabdominal ultrasonography
• ISSN: 1930-0433; 1930-0433
• DOI: 10.1016/j.radcr.2024.06.026

We herein report a case of sporadic intra-abdominal desmoid-type fibromatosis in which contrast-enhanced ultrasonography (US) combined with superb microvascular imaging (SMI) was useful for preoperative diagnosis. 18-Fluorodeoxyglucose positron emission tomography performed for systematic screening for lung cancer revealed an abnormal accumulation in the abdominal cavity. Transabdominal US showed a tumor with a mixture of hypoechoic and hyperechoic areas. Contrast-enhanced US combined with SMI revealed dendritic blood flow signals and no abnormal vascular network within the tumor. Macroscopic examination of the resected specimen revealed a white tumor with relatively clear boundaries. Microscopic examination revealed spindle cells with poor atypia proliferating in bundles with collagenous stromal cells. Immunohistochemistry showed nuclear localization of beta-catenin within the tumor cells. From these findings, we finally diagnosed intra-abdominal desmoid-type fibromatosis. Contrast-enhanced US combined with SMI is useful for diagnosing intra-abdominal desmoid-type fibromatosis.