Phytochemistry and Biological Activities of Murraya Species

is a plant genus within the Rutaceae family comprising over 17 species, which are widely distributed in Asia, Australia, and the Pacific Islands. Furthermore, these species have been used in traditional medicine to treat fever, pain, and dysentery. Several reports have also extensively studied the l...

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2023-08, Vol.28 (15), p.5901
Main Authors: Yohanes, Ricky, Harneti, Desi, Supratman, Unang, Fajriah, Sofa, Rudiana, Tarso
Format: Article
Language:English
Subjects:
Alkaloids
Cytotoxicity
Ethnopharmacology
Medicine, Traditional
Metabolites
Murraya
Phytochemicals
Phytochemicals - chemistry
Phytochemicals - pharmacology
phytochemistry
Phytotherapy
Plant Extracts - chemistry
Plant Extracts - pharmacology
Review
Rutaceae
secondary metabolites
Seeds
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Summary:is a plant genus within the Rutaceae family comprising over 17 species, which are widely distributed in Asia, Australia, and the Pacific Islands. Furthermore, these species have been used in traditional medicine to treat fever, pain, and dysentery. Several reports have also extensively studied the leaves, seeds, stembark, and bark of from 1965 to 2023 to explore their natural product composition. Various phytochemical studies have revealed the isolation of 413 compounds recorded, comprising coumarins, terpenoids, flavonoids, and aromatics, as well as alkaloids, which constitute the largest proportion (46.9%). These isolated compounds have long been known to exhibit different bioactivities, such as cytotoxic and anti-inflammatory properties. Cytotoxic activity has been observed against HCT 116, HeLa, HepG2, and other cell lines. Previous studies have also reported the presence of antifungal, hepatoprotective, antihyperlipidemic, antidiarrheal, and antioxidant effects. Therefore, this review provides a comprehensive overview of species, highlighting their phytochemistry, biological activities, and potential as a source of active natural compounds.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules28155901