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Short‐term evaluation of renal markers in overweight adult cats
Background Obesity has been proposed as an independently risk factor for chronic kidney disease (CKD) in people, but its role in feline kidney function is unknown. Objective Obesity has been proposed as an independent risk factor for chronic kidney disease (CKD) in people, but its role in feline kid...
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Published in: | Veterinary medicine and science 2023-03, Vol.9 (2), p.572-578 |
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Main Authors: | , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites |
Online Access: | Get full text |
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Summary: | Background
Obesity has been proposed as an independently risk factor for chronic kidney disease (CKD) in people, but its role in feline kidney function is unknown.
Objective
Obesity has been proposed as an independent risk factor for chronic kidney disease (CKD) in people, but its role in feline kidney function is unknown. This study prospectively evaluated the effect of overweight on the concentration of symmetric dimethylarginine (SDMA) and creatinine in a cohort of healthy cats.
Methods
Forty healthy adult cats were included, 14 with a body condition score (BCS) = 5 and 26 with a BCS > 5. Cats were examined every 6 months, for up to 12 months. SDMA and creatinine were measured at baseline and follow‐up.
Results
No effect was found for time of follow‐up (p = 0.072), overweight (p = 0.9442) or their interaction (p = 0.902) on SDMA, though a significant effect was found for age (p < 0.001) [older cats showing higher SDMA] and sex (p = 0.007) [male cats showing higher SDMA]. Regarding creatinine, no effect for time (p = 0.671), age (p = 0.061), overweight (p = 0.319) or the latter's interaction (p = 0.386) were found.
Conclusions
In the short term, markers of renal function did not show an association with overweight. The role of obesity in feline kidney function still warrants further evaluation. |
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ISSN: | 2053-1095 2053-1095 |
DOI: | 10.1002/vms3.1021 |