Delay in specimen processing-major source of preanalytical variation in serum electrolytes

To evaluate the stability of electrolytes in serum samples due to delay in analysis in a tertiary care government hospital in India, and the maximum time delay acceptable between sample centrifugation and analysis. We estimated serum electrolytes of 400 samples with different time intervals between...

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Bibliographic Details
Published in:Journal of clinical and diagnostic research 2014-12, Vol.8 (12), p.CC01-CC03
Main Authors: Baruah, Ankur, Goyal, Parul, Sinha, Saket, Ramesh, K L, Datta, Rashmirasi
Format: Article
Language:English
Subjects:
acceptable limit change
Biochemistry Section
sample stability
serum electrolyte
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Summary:To evaluate the stability of electrolytes in serum samples due to delay in analysis in a tertiary care government hospital in India, and the maximum time delay acceptable between sample centrifugation and analysis. We estimated serum electrolytes of 400 samples with different time intervals between centrifugation and sample analysis on automated analyser. Values were compared using repeated measure ANNOVA and acceptable limit change using in house QC values of 6 months. During the time interval between centrifugation and sample analysis, the samples were kept uncovered in sample cups in the laboratory. Potassium values show significant changes within 1 h (T1, p
ISSN:2249-782X
0973-709X
DOI:10.7860/JCDR/2014/10150.5285