Hepatitis E Prevalence in Vulnerable Populations in Goiânia, Central Brazil

A transversal study was conducted among 472 vulnerable individuals (recyclable waste pickers, immigrants and refugees, homeless individuals, as well as lesbian, gay, bisexual, and transexual individuals) in Goiânia City, the capital of the State of Goiás, Brazil, to investigate the prevalence of hep...

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Bibliographic Details
Published in:Viruses 2023-10, Vol.15 (10), p.2070
Main Authors: Teles, Sheila Araújo, Caetano, Karlla Antonieta Amorim, Carneiro, Megmar Aparecida dos Santos, Villar, Livia Melo, Stacciarini, Jeanne-Marie, Martins, Regina Maria Bringel
Format: Article
Language:English
Subjects:
Blood & organ donations
Brazil
Brief Report
Chemiluminescence
DNA-directed RNA polymerase
Education
Epidemiology
Genotype & phenotype
Health aspects
Hepatitis
Hepatitis E
hepatitis E virus
Immunoassay
Immunoglobulin G
Immunoglobulin M
Immunoglobulins
Infections
Liver cirrhosis
Low income groups
Minorities
Mortality
Pregnancy
prevalence
Public health
Refugees
Ribonucleic acid
Risk factors
RNA
Serology
Severe acute respiratory syndrome coronavirus 2
Socially handicapped
Statistics
Vaccines
Viruses
vulnerable populations
Zoonoses
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Summary:A transversal study was conducted among 472 vulnerable individuals (recyclable waste pickers, immigrants and refugees, homeless individuals, as well as lesbian, gay, bisexual, and transexual individuals) in Goiânia City, the capital of the State of Goiás, Brazil, to investigate the prevalence of hepatitis E virus (HEV) infection. A total of 459 (97.2%) serum samples were tested for anti-HEV IgG and IgM antibodies using fully automated chemiluminescence immunoassays (Liaison® Murex Anti-HEV IgG and IgM assays, DiaSorin, Saluggia, Italy). Positive samples were tested for the presence of HEV RNA by a real-time polymerase chain reaction. A seroprevalence of 0.87% (95% confidence interval [CI]: 0.34–2.22) was found for anti-HEV IgG. Furthermore, anti-HEV IgM was detected in only one individual (0.22%; 95% CI: 0.04–1.22), who was also negative for HEV RNA. These findings revealed that HEV infection is infrequent in vulnerable individuals in Central Brazil, with low seroprevalence of past and recent HEV infections.
ISSN:1999-4915
1999-4915
DOI:10.3390/v15102070