Efficacy of Aloe vera, Ananas comosus, and Sansevieria masoniana Cream on the Skin Wound Infected with MRSA

The tropical area has a lot of herbal medicines such as Aloe vera (AV), Ananas comosus (AC), and Sansevieria masoniana (SM). All the three have a unique potential effect as an antibacterial and wound-healing promoter. The aim of this study is to explore the role of AV, AC, and SM on the skin wound i...

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Bibliographic Details
Published in:Advances in Pharmacological Sciences 2018-01, Vol.2018 (2018), p.1-7
Main Authors: Prakoso, Yos Adi, Wirjaatmadja, Roeswandono, Setiyo Rini, Chylen
Format: Article
Language:English
Subjects:
Angiogenesis
Antibacterial agents
Antimicrobial agents
Collagen
Dermatologic agents
Dermatology
Fibroblasts
Flavonoids
Formulae, receipts, prescriptions
Histopathology
Laboratory animals
Medicine, Botanic
Medicine, Herbal
Pharmaceutical sciences
Pharmacology
Phenols
Phytochemicals
Skin
Staphylococcus aureus
Staphylococcus aureus infections
Staphylococcus infections
Tensile strength
Wound healing
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Summary:The tropical area has a lot of herbal medicines such as Aloe vera (AV), Ananas comosus (AC), and Sansevieria masoniana (SM). All the three have a unique potential effect as an antibacterial and wound-healing promoter. The aim of this study is to explore the role of AV, AC, and SM on the skin wound infected with methicillin-resistant Staphylococcus aureus (MRSA). Forty-five adult female Sprague Dawley rats weighing 250–300 grams were divided into 5 groups. All the groups were exposed to two round full-thickness punch biopsy and infected with MRSA. The group C was the control group/untreated; group BC was treated with base cream/without extract; group AV was treated with 75% AV cream; group AC was treated with 75% AC cream, and group SM was treated with 75% SM cream. The wounds were observed on days 5, 10, and 15. The healing of skin wounds was measured by a percentage of closure, skin tensile strength, and histopathology. The result showed that AV, AC, and SM have a similar potential effect on healing in the wound that was infected with MRSA compared to the groups C and BC (P
ISSN:2633-4682
1687-6334
2633-4690
1687-6342
DOI:10.1155/2018/4670569