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Evaluation of Bispectral Index time delay in response to anesthesia induction: an observational study

According to the manufacturer, the Bispectral Index (BIS) has a processing time delay of 5–10s. Studies addressing this have suggested longer delays. We evaluated the time delay in the Bispectral Index response. Based on clinical data from 45 patients, using the difference between the predicted and...

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Bibliographic Details
Published in:Brazilian journal of anesthesiology (Elsevier) 2019-07, Vol.69 (4), p.377-382
Main Authors: Ferreira, Ana Leitão, Mendes, Joaquim Gabriel, Nunes, Catarina Sofia, Amorim, Pedro
Format: Article
Language:English
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Summary:According to the manufacturer, the Bispectral Index (BIS) has a processing time delay of 5–10s. Studies addressing this have suggested longer delays. We evaluated the time delay in the Bispectral Index response. Based on clinical data from 45 patients, using the difference between the predicted and the real BIS, calculated during a fixed 3minutes period after the moment the Bispectral Index dropped below 80 during the induction of general anesthesia with propofol and remifentanil. The difference between the predicted and the real BIS was in average 30.09±18.73s. Our results may be another indication that the delay in BIS processing may be much longer than stated by the manufacture, a fact with clinical implications. De acordo com o fabricante, o índice bispectral (BIS) tem um tempo de processamento de cinco a dez segundos. Estudos que avaliaram esse tempo de processamento sugeriram atrasos mais longos. Nós avaliamos o tempo de atraso na resposta do BIS. Com base em dados clínicos de 45 pacientes, calculamos a diferença entre o tempo de atraso previsto e real do índice bispectral durante um período fixo de três minutos após o momento em que o BIS caiu abaixo de 80 durante a indução da anestesia geral com propofol e remifentanil. A diferença entre o BIS previsto e real foi em média 30,09±18,73 segundos. Nossos resultados sugerem que o atraso no processamento do índice bispectral pode ser muito maior que o declarado pelo fabricante, um fato com implicações clínicas.
ISSN:0104-0014
1806-907X
0104-0014
DOI:10.1016/j.bjane.2019.04.006