Sex Linked Differences in Blood Pressure Indices of COVID-19 Patients After Six Minute Walk Test

Objective: The study was aimed to assess the sex-linked differences in the Blood Pressure Indices (BPI) i.e., Mean Arterial Pressure (MAP) and Pulse Pressure (PP) of COVID patients after 6 Minute Walk Test (6MWT). Study type, settings and duration: This observational study was conducted in the Insti...

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Bibliographic Details
Published in:Pakistan journal of medical research 2024-03, Vol.63 (1), p.30
Main Authors: Raza, Syed Shahmeer, Khalid, Laila, Fida, Najma, Ali, Dur e Shehwar, Zafar, Umema, Ali, Haya
Format: Article
Language:English
Subjects:
Blood pressure
cardiac physiology
Cardiovascular diseases
COVID
COVID-19
Demographic aspects
Diagnosis
Exercise tests
Females
gender
Gender differences
Heart rate
Infections
Males
Measurement
Medical research
Medicine, Experimental
Methods
Mortality
Pandemics
Risk factors
Variables
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Summary:Objective: The study was aimed to assess the sex-linked differences in the Blood Pressure Indices (BPI) i.e., Mean Arterial Pressure (MAP) and Pulse Pressure (PP) of COVID patients after 6 Minute Walk Test (6MWT). Study type, settings and duration: This observational study was conducted in the Institute of Basic Medical Sciences, Khyber Medical University, Peshawar from December 2021 to April 2022. Methodology: There were 54 participants (21 Females and 33 Males). Participants with previous COVID-19 infection with a cut off of 3 months post COVID, were included in the study. The participant's Heart Rate and Blood Pressure were recorded both before and after performing 6MWT. Results: Both pre and post stress comparison of mean difference between post COVID males and females, was significant for MAP (Post-Stress p =0.002 and Pre-Stress p =0.01) only. PP and HR did not show any significant differences between the males vs females in both pre and post stress phase. While, post COVID females had a higher HR than males in both pre and post phase. General Linear regression model was developed while controlling for age and to check the relation between MAP, PP and HR. R squared came out to be 0.648 while MAP was significant with a p value = 0.012. Conclusion: This study found a significant difference in Mean Arterial Pressure (MAP) between male and female COVID-19 patients after a 6-minute walk test, suggesting sex-based variations in blood pressure response post-infection. Further research with larger samples is needed to explore the clinical implications of this finding.
ISSN:0030-9842