Central Arterial Hemodynamic Effects of Dark Chocolate Ingestion in Young Healthy People: A Randomized and Controlled Trial

• Published in: Cardiology Research and Practice 2014-01, Vol.2014 (2014), p.z1-7
• Main Authors: Maldonado, J., Pereira, T., Laranjeiro, M., Coutinho, R., Cardoso, E., Andrade, I., Conde, J.
• Format: Article
• Language: English
• Subjects: Arteries; Blood pressure; Cardiovascular disease; Chocolate; Clinical Study; Cocoa; College students; Endothelium; Flavonoids; Food and nutrition; Health aspects; Health care; Hemodynamics; Medical research; Medicine, Experimental; Statistical analysis; Veins & arteries; Young adults
• ISSN: 2090-0597; 2090-8016; 2090-0597
• DOI: 10.1155/2014/945951

Introduction. The aim of this study was to assess the vascular benefits of dark chocolate in healthy and young individuals. Methods. A randomized and controlled trial was carried out involving 60 healthy volunteers, randomized into two groups: control group (CG; n=30) and intervention group (IG; n=30). The IG ingested a daily dosage of 10 g of dark chocolate (>75% cocoa) for a month. Blood pressure (BP), flow-mediated dilation (FMD), arterial stiffness index (ASI), aortic pulse wave velocity (PWV), and pulse wave analysis (PWA) were assessed at baseline and one week after the one-month intervention period. Results. Arterial function improved after intervention in the IG, with PWV decreasing from 6.13±0.41 m/s to 5.83±0.53 m/s (P=0.02), with no significant differences observed in the CG. A significant decrease in ASI (0.16±0.01 to 0.13±0.01; P