Retrospective Description of Pregnant Women Infected with Severe Acute Respiratory Syndrome Coronavirus 2, France

• Published in: Emerging infectious diseases 2020-09, Vol.26 (9), p.2069-2076
• Main Authors: Vivanti, Alexandre J, Mattern, Jérémie, Vauloup-Fellous, Christelle, Jani, Jacques, Rigonnot, Luc, El Hachem, Larissa, Le Gouez, Agnès, Desconclois, Céline, Ben M'Barek, Imane, Sibiude, Jeanne, Benachi, Alexandra, Picone, Olivier, Cordier, Anne-Gaël
• Format: Article
• Language: English
• Subjects: Adult; Betacoronavirus; Body mass index; Coronavirus Infections - complications; Coronavirus Infections - transmission; Coronavirus Infections - virology; Coronaviruses; COVID-19; Disease transmission; Dyspnea; Expedited; Female; Gestational age; Hospitalization; Hospitalization - statistics & numerical data; Humans; Infections; Infectious Disease Transmission, Vertical; Intensive care; Intensive Care Units; Laboratories; Medical records; Obstetrics; Oxygen therapy; Pandemics; Paris; Patients; Pneumonia, Viral - complications; Pneumonia, Viral - transmission; Pneumonia, Viral - virology; Pregnancy; Pregnancy Complications, Infectious - virology; Pregnancy Outcome; Pregnant women; respiratory infections; Retrospective Description of Pregnant Women Infected with Severe Acute Respiratory Syndrome Coronavirus 2, France; Retrospective Studies; SARS; SARS-CoV-2; Severe acute respiratory syndrome; Severe acute respiratory syndrome coronavirus 2; Statistical analysis; Thermal cycling; Womens health
• ISSN: 1080-6040; 1080-6059
• DOI: 10.3201/eid2609.202144

Fix data are available on the management of pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We conducted a retrospective study of 100 pregnant women with SARS-CoV-2 infection in 4 obstetric units in the Paris metropolitan area of France during March 12-April 13, 2020. Among patients, 52 (52%) were hospitalized, 10 (10%) in intensive care units (ICUs). Women with higher body mass indexes (BMIs; median 30.7 kg/m ) were more likely to be hospitalized in ICUs than other women (median BMI 26.2 kg/m ). Women hospitalized in ICUs had lower lymphocyte count at diagnosis (median 0.77 × 10 cells/L) than women not hospitalized in ICUs (median lymphocyte count 1.15 × 10 cells/L). All women requiring oxygen >5 L/min were intubated. Clinical and laboratory evaluation of SARS-CoV-2-positive pregnant women at the time of diagnosis can identify patients at risk for ICU hospitalization.