Type 2 diabetes is an independent predictor of lowered peak aerobic capacity in heart failure patients with non-reduced or reduced left ventricular ejection fraction

Although type 2 diabetes mellitus (T2DM) is one of the most frequent comorbidities in patients with chronic heart failure (CHF), the effects of T2DM on the exercise capacity of CHF patients are fully unknown. Here, we tested the hypothesis that the coexistence of T2DM lowers CHF patients' peak...

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Published in:Cardiovascular diabetology 2020-09, Vol.19 (1), p.142-142, Article 142
Main Authors: Abe, Takahiro, Yokota, Takashi, Fukushima, Arata, Kakutani, Naoya, Katayama, Takashi, Shirakawa, Ryosuke, Maekawa, Satoshi, Nambu, Hideo, Obata, Yoshikuni, Yamanashi, Katsuma, Nakano, Ippei, Takada, Shingo, Yokota, Isao, Okita, Koichi, Kinugawa, Shintaro, Anzai, Toshihisa
Format: Article
Language:English
Subjects:
Exercise
Heart failure
Original Investigation
Oxygen uptake
Type 2 diabetes
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Summary:Although type 2 diabetes mellitus (T2DM) is one of the most frequent comorbidities in patients with chronic heart failure (CHF), the effects of T2DM on the exercise capacity of CHF patients are fully unknown. Here, we tested the hypothesis that the coexistence of T2DM lowers CHF patients' peak aerobic capacity. We retrospectively analyzed the cases of 275 Japanese CHF patients with non-reduced ejection fraction (left ventricular ejection fraction [LVEF] ≥ 40%) or reduced EF (LVEF 
ISSN:1475-2840
1475-2840
DOI:10.1186/s12933-020-01114-4