Prostate Cancer Biochemical Recurrence Resulted Negative on [ 68 Ga]Ga-PSMA-11 but Positive on [ 18 F]Fluoromethylcholine PET/CT

For prostate cancer (PCa) biochemical recurrence (BCR), the primarily suggested imaging technique by the European Association of Urology (EAU) guidelines is prostate-specific membrane antigen (PSMA) positron emission tomography/computer tomography (PET/CT). Indeed, the increased detection rate of PS...

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Bibliographic Details
Published in:Tomography (Ann Arbor) 2022-09, Vol.8 (5), p.2471-2474
Main Authors: Laudicella, Riccardo, La Torre, Flavia, Davì, Valerio, Crocè, Ludovica, Aricò, Demetrio, Leonardi, Giuseppe, Russo, Simona, Minutoli, Fabio, Burger, Irene A, Baldari, Sergio
Format: Article
Language:English
Subjects:
biochemical recurrence
Case Report
Choline
Computers
Gallium Radioisotopes
Humans
Male
PET
Positron Emission Tomography Computed Tomography - methods
Positron-Emission Tomography
prostate cancer
Prostatic Neoplasms - diagnostic imaging
PSMA
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Summary:For prostate cancer (PCa) biochemical recurrence (BCR), the primarily suggested imaging technique by the European Association of Urology (EAU) guidelines is prostate-specific membrane antigen (PSMA) positron emission tomography/computer tomography (PET/CT). Indeed, the increased detection rate of PSMA PET/CT for early BCR has led to a fast and wide acceptance of this novel technology. However, PCa is a very heterogeneous disease, not always easily assessable with the highly specific PSMA PET with around 10% of cases occuring without PSMA expression. In this paper, we present the case of a patient with PCa BCR that resulted negative on [ Ga]Ga-PSMA-11 PET/CT, but positive on [ F]Fluoromethylcholine (Choline) PET/CT.
ISSN:2379-139X
2379-1381
2379-139X
DOI:10.3390/tomography8050205