The serum C Peptide levels among the offsprings of the people with type 2 diabetes

Insulin Resistance (IR) is a condition in which the cells of the body become resistant to the effect of insulin , that is, the normal response to a given amount of insulin is reduced. As a result, levels of insulin are needed in order for insulin to produce its effect. The incidence of diabetes in t...

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Published in:Journal of clinical and diagnostic research 2013-05, Vol.7 (5), p.827-830
Main Authors: Kumar, Gaurav, Kumar, Jayballabh, Khan, Farhan Ahmad, Kumar, Devesh, Malik, Kiran
Format: Article
Language:English
Subjects:
c-peptide
diabetes mellitus
insulin resistance
obesity
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Summary:Insulin Resistance (IR) is a condition in which the cells of the body become resistant to the effect of insulin , that is, the normal response to a given amount of insulin is reduced. As a result, levels of insulin are needed in order for insulin to produce its effect. The incidence of diabetes in the offsprings of diabetic couples was more than the incidence of diabetes in the offsprings, of whom only a single parent was diabetic. This study was done to assess the prevalence of insulin resistance in the offsprings of diabetic patients. The present, cross sectional study conducted in the Teerthanker Mahaveer Medical College and Research Centre, Moradabad, U.P., india. The offsprings of diabetic subjects attended the General Medicine OPD and the Diabetic Clinic and they were also admitted in the indoor wards of the Department of Medicine. The study material consisted of 53 (35 males and 18 females) live offsprings of diabetics from 28 families. The mean c-peptide level in the offsprings of biparental diabetics was significantly higher than that in the offsprings of monoparental diabetics (p
ISSN:2249-782X
0973-709X
DOI:10.7860/JCDR/2013/5498.2951