The Relationship Between the Triglyceride-Glucose Index and Cryptogenic Stroke in Patients with Patent Foramen Ovale

Objective This study aimed to investigate the association between the triglyceride-glucose (TyG) index and cryptogenic stroke (CS) in patients diagnosed with patent foramen ovale (PFO) using transesophageal echocardiography (TEE). Methods A retrospective, single-center study was conducted at a terti...

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Bibliographic Details
Published in:Clinical and applied thrombosis/hemostasis 2024-01, Vol.30, p.10760296241301411
Main Authors: Esin, Fatma, Ince, Hüseyin Sefa, Aktürk, Semih, Citekci, Fahrettin Tugrul, Celik, Aykan, Kocabas, Ugur, Kiris, Tuncay, Karaca, Mustafa
Format: Article
Language:English
Subjects:
Adult
Blood Glucose - analysis
Echocardiography, Transesophageal
Female
Foramen Ovale, Patent - blood
Foramen Ovale, Patent - complications
Glucose
Humans
Ischemic Stroke - blood
Ischemic Stroke - etiology
Male
Middle Aged
Original
Retrospective Studies
Stroke - blood
Stroke - etiology
Triglycerides - blood
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Summary:Objective This study aimed to investigate the association between the triglyceride-glucose (TyG) index and cryptogenic stroke (CS) in patients diagnosed with patent foramen ovale (PFO) using transesophageal echocardiography (TEE). Methods A retrospective, single-center study was conducted at a tertiary education and research hospital from January 2015 to December 2023. The study population included 1017 consecutive patients with sinus rhythm diagnosed with PFO, of whom 210 had CS. The TyG Index was calculated using triglyceride and fasting glucose levels. Results Patients with CS were older (47.53 ± 12.34 years) compared to control group (44.40 ± 17.82 years, p = .005). The proportion of males was higher in the CS group (56.2%) compared to the control group (48.3%, p = .042). Laboratory findings revealed higher TyG Index (8.87 ± 0.51 vs 8.63 ± 0.55, p 
ISSN:1076-0296
1938-2723
1938-2723
DOI:10.1177/10760296241301411