An Unusual Small Bowel Lesion

Immunohistochemically, the tumor cells were positive for α-smooth muscle actin, desmin, and h-caldesmon, and negative for CD117, CK AE1/AE3, and S-100 protein. [...]a stage IV leiomyosarcoma was diagnosed. [...]intussusception often reduces spontaneously, although it can recur [3]. The most commonly...

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Bibliographic Details
Published in:GE Portuguese journal of gastroenterology 2020-08, Vol.27 (5), p.372-374
Main Authors: Costa-Santos, Maria Pia, Moreira-Pinto, João, Oliveira, Maria Helena, Oliveira Ferreira, Alexandre
Format: Article
Language:English
Subjects:
Chemotherapy
Endoscopy
Images in Gastroenterology and Hepatology
Intestinal obstruction
leiomyosarcoma
Metastasis
Sarcoma
small bowel
Small intestine
Smooth muscle
upper gastrointestinal bleeding
Uterus
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Summary:Immunohistochemically, the tumor cells were positive for α-smooth muscle actin, desmin, and h-caldesmon, and negative for CD117, CK AE1/AE3, and S-100 protein. [...]a stage IV leiomyosarcoma was diagnosed. [...]intussusception often reduces spontaneously, although it can recur [3]. The most commonly used drugs as initial treatment in metastatic soft tissue sarcomas – doxorubicin and ifosfamide – show limited efficacy for leiomyosarcoma, with response rates between 10 and 25% [1, 2].
ISSN:2341-4545
2387-1954
DOI:10.1159/000505272