The recent advances, drawbacks, and the future directions of CMRI in the diagnosis of IHD

• Published in: Scientific reports 2021-07, Vol.11 (1), p.14958-14958, Article 14958
• Main Authors: Fagiry, Moram A., Abdelaziz, Ikhlas, Davidson, Rob, Mahmoud, Mustafa Z.
• Format: Article
• Language: English
• Subjects: 692/308; 692/4019; 692/699; Angiography; Cardiovascular disease; Cardiovascular diseases; Coronary artery; Coronary artery disease; Diagnosis; Heart diseases; Heart rate; Humanities and Social Sciences; Ischemia; Magnetic resonance imaging; Morbidity; multidisciplinary; Perfusion; Science; Science (multidisciplinary); Ventricle
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-021-94311-4

Ischemic heart disease (IHD), also known as coronary artery disease (CAD), is a leading cause of morbidity and mortality in adults. The aims of this research were to study the recent advances on the prognostic and diagnostic value, drawbacks, and the future directions of cardiac magnetic resonance imaging (CMRI) in the diagnosis of IHD. One hundred patients with IHD who had been clinically diagnosed were enrolled in this study prospectively. CMRI; Siemens Magnetom Sola 1.5 T MRI scanner was used to examine the patients. To confirm the diagnosis, conventional coronary angiography was used. CMRI revealed that the left ventricular (LV) volumes and systolic function of male and female patients differed by age decile were 28.9 ± 3.5%; 32 ± 1.7%, 53.3 ± 11.2; 58 ± 6.6 ml, 100.6 ± 7.1; 98.3 ± 14.7 bpm, 5.4 ± 1.4; 5.8 ± 1.5 L/min, 189 ± 14.3; 180 ± 10.9 ml, and 136 ± 3.1; 123 ± 4.4 ml for the left ventricle ejection fraction (LVEF), stroke volume (SV), heart rate, cardiac output, end diastolic volume (EDV), and end systolic volume (ESV), respectively. CMRI has sensitivity, specificity, and accuracy of 97%, 33.33%, and 95.15%, respectively. Finally, CMRI provides a comprehensive assessment of LV function, myocardial perfusion, and viability, as well as coronary anatomy.