Levodopa Prescription Patterns in Patients with Advanced Parkinson’s Disease: A Japanese Database Analysis

Prescription doses of levodopa in patients with advanced Parkinson’s disease (PD) are generally lower in Japan than in the United States or Europe, although Japanese guidelines for the management of PD recommend increasing the dosage as the disease progresses. However, data regarding levodopa prescr...

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Bibliographic Details
Published in:Parkinson's disease 2023-09, Vol.2023, p.1-13
Main Authors: Takeda, Atsushi, Baba, Toru, Watanabe, Jun, Nakayama, Masahiko, Hozawa, Hiroyuki, Ishido, Miwako
Format: Article
Language:English
Subjects:
Activities of daily living
Agonists
Analysis
Antiparkinsonian agents
Body weight
Cognitive ability
Demographics
Disease
Dopamine
Dosage
Drug dosages
Hospital patients
Hospitalization
Hospitals
Levodopa
Light-emitting diodes
Medical advice systems
Medical research
Medicine, Experimental
Movement disorders
Neurodegenerative diseases
Parkinson's disease
Patients
Payment systems
Prescription drugs
Reimbursement
Statistical significance
Citations: Items that this one cites
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Summary:Prescription doses of levodopa in patients with advanced Parkinson’s disease (PD) are generally lower in Japan than in the United States or Europe, although Japanese guidelines for the management of PD recommend increasing the dosage as the disease progresses. However, data regarding levodopa prescription practices in patients with advanced PD in the clinical setting are limited. This retrospective observational study analyzed patterns of drug use for patients with advanced PD in Japan using claims data from hospitalized patients in the Medical Data Vision Co. database. Eligible patients had at least two PD-associated claims in two different quarters between April 1, 2008, and November 30, 2018, and a 10-item activities of daily living score
ISSN:2090-8083
2042-0080
DOI:10.1155/2023/9404207