Drastic improvement of cardiac function after living-donor renal transplantation in a long-term hemodialysis patient with severe mitral regurgitation

Background Although there are reports of recovery of cardiac function after renal transplantation, the feasibility of renal transplantation in patients with low cardiac function remains controversial. Case presentation A 59-year-old Japanese male was scheduled to undergo living-donor renal transplan...

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Bibliographic Details
Published in:JA clinical reports 2022-12, Vol.8 (1), p.95-95, Article 95
Main Authors: Noguchi, Satoko, Saito, Junichi, Hashiba, Eiji, Hirota, Kazuyoshi
Format: Article
Language:English
Subjects:
Anemia
Anesthesiology
Angina pectoris
Cardiac function
Case Report
Case reports
Creatinine
Critical Care Medicine
Ejection fraction
Emergency Medicine
General anesthesia
Heart surgery
Hemodialysis
Hemoglobin
Intensive
Kidney diseases
Kidney transplants
Long-term hemodialysis
Medicine
Medicine & Public Health
Mitral regurgitation
Pain Medicine
Patients
Peptides
Pulmonary arteries
Renal transplantation
Veins & arteries
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Summary:Background Although there are reports of recovery of cardiac function after renal transplantation, the feasibility of renal transplantation in patients with low cardiac function remains controversial. Case presentation A 59-year-old Japanese male was scheduled to undergo living-donor renal transplantation (LDRT) under general anesthesia. Preoperative transthoracic echocardiography revealed severe mitral regurgitation (MR) and a left ventricular ejection fraction (LVEF) at 30%. LDRT was conducted prior to cardiac surgery with restrictive fluid management and close monitoring of cardiac function. The patient’s renal function improved promptly after the LDRT, and his hemodynamics were stable throughout the perioperative period. Along with improvements in the patient’s renal function and anemia, the patient’s cardiac function improved to LVEF 50% and achieved drastically improved MR as well as cardiac function, without intervention. Conclusion This case indicates that LDRT has the potential to improve cardiac function in patients who have been on hemodialysis for more than 20 years.
ISSN:2363-9024
2363-9024
DOI:10.1186/s40981-022-00583-8