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Incidence and predictors of surgical site infection after ORIF in calcaneus fractures, a retrospective cohort study
Occurrence of calcaneus fractures is on the up trend. Owing to its unique anatomical morphology and limited soft-tissue envelope, management of calcaneus fractures is a challenge to the orthopaedic surgeon, and surgical site infection (SSI) is one of the serious postoperative complications. In order...
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Published in: | Journal of orthopaedic surgery and research 2018-11, Vol.13 (1), p.293-293, Article 293 |
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description | Occurrence of calcaneus fractures is on the up trend. Owing to its unique anatomical morphology and limited soft-tissue envelope, management of calcaneus fractures is a challenge to the orthopaedic surgeon, and surgical site infection (SSI) is one of the serious postoperative complications. In order to decrease the incidence of wound breakdown and improve clinical outcomes, it is necessary to understand which factors were associated with SSI. The aim of this study was to identify predictors of SSI and quantify the incidence of SSI in calcaneus fractures following open reduction and internal fixation (ORIF).
This retrospective study was performed at a level 1 trauma center from January 2014 to June in 2017. Data of adult patients with calcaneus fractures treated by ORIF were extracted from the electronic medical records. A total of 681 patients were collected. We reviewed the patients' demographics, characteristics of fracture, treatment-related variables, and indexes of laboratory examination. Univariate and multivariate logistic analysis models were performed respectively to determine independent predictors of SSI.
Sixty-six patients developed SSI in this study. The overall incidence of SSI after ORIF of calcaneus fracture was 9.7%, with 2.9% for deep infection and 6.8% for superficial SSI. Independent predictors of SSI identified by multivariate analysis were open fracture (odds ratio = 9.48, 95% CI = 4.53-19.85, P = 0.00007), high-energy injury (odds ratio = 2.07, 95% CI = 1.16-3.70, P = 0.01437), ASA class 3 or higher (odds ratio = 3.50, 95% CI = 1.18-10.37, P = 0.02401), and intraoperative temperature |
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This retrospective study was performed at a level 1 trauma center from January 2014 to June in 2017. Data of adult patients with calcaneus fractures treated by ORIF were extracted from the electronic medical records. A total of 681 patients were collected. We reviewed the patients' demographics, characteristics of fracture, treatment-related variables, and indexes of laboratory examination. Univariate and multivariate logistic analysis models were performed respectively to determine independent predictors of SSI.
Sixty-six patients developed SSI in this study. The overall incidence of SSI after ORIF of calcaneus fracture was 9.7%, with 2.9% for deep infection and 6.8% for superficial SSI. Independent predictors of SSI identified by multivariate analysis were open fracture (odds ratio = 9.48, 95% CI = 4.53-19.85, P = 0.00007), high-energy injury (odds ratio = 2.07, 95% CI = 1.16-3.70, P = 0.01437), ASA class 3 or higher (odds ratio = 3.50, 95% CI = 1.18-10.37, P = 0.02401), and intraoperative temperature < 36.0 °C (odds ratio = 1.69, 95% CI = 1.13-2.28, P = 0.04410).
The SSI incidence was high (9.7%) for calcaneus fractures following ORIF. External fixation plays an important role in the treatment of severely displaced and depressed intra-articular or open calcaneus fractures. Increased ASA class and intraoperative hypothermia were associated with wound breakdown, and elaborative evaluation of fracture and soft-tissue damage was vitally necessary in this at-risk population.</description><identifier>ISSN: 1749-799X</identifier><identifier>EISSN: 1749-799X</identifier><identifier>DOI: 10.1186/s13018-018-1003-y</identifier><identifier>PMID: 30458814</identifier><language>eng</language><publisher>England: BioMed Central</publisher><subject>Adolescent ; Adult ; Aged ; Ankle ; Calcaneus ; Calcaneus - injuries ; Calcaneus - surgery ; Calcaneus fracture ; Cardiovascular disease ; Cohort analysis ; Cohort Studies ; Demography ; Diabetes ; Electronic medical records ; Female ; Fracture Fixation, Internal - adverse effects ; Fracture Fixation, Internal - trends ; Fractures ; Fractures, Bone - diagnosis ; Fractures, Bone - surgery ; Hospitals ; Humans ; Hypothermia ; Incidence ; Infections ; Male ; Medical records ; Middle Aged ; Multivariate analysis ; Open Fracture Reduction - adverse effects ; Open Fracture Reduction - trends ; Orthopedics ; Patients ; Predictive Value of Tests ; Retrospective Studies ; Risk factors ; Substance abuse treatment ; Surgeons ; Surgery ; Surgical site infection ; Surgical site infections ; Surgical Wound Infection - diagnosis ; Surgical Wound Infection - epidemiology ; Trauma ; Wounds ; Young Adult</subject><ispartof>Journal of orthopaedic surgery and research, 2018-11, Vol.13 (1), p.293-293, Article 293</ispartof><rights>Copyright © 2018. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s). 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c493t-7677bd1918b78003ac0d4b4d4743414390e1ffecd8181d2f3611aa89cdafff573</citedby><cites>FETCH-LOGICAL-c493t-7677bd1918b78003ac0d4b4d4743414390e1ffecd8181d2f3611aa89cdafff573</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245558/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2158384130?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30458814$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Hui</creatorcontrib><creatorcontrib>Pei, Honglei</creatorcontrib><creatorcontrib>Chen, Meiyun</creatorcontrib><creatorcontrib>Wang, He</creatorcontrib><title>Incidence and predictors of surgical site infection after ORIF in calcaneus fractures, a retrospective cohort study</title><title>Journal of orthopaedic surgery and research</title><addtitle>J Orthop Surg Res</addtitle><description>Occurrence of calcaneus fractures is on the up trend. Owing to its unique anatomical morphology and limited soft-tissue envelope, management of calcaneus fractures is a challenge to the orthopaedic surgeon, and surgical site infection (SSI) is one of the serious postoperative complications. In order to decrease the incidence of wound breakdown and improve clinical outcomes, it is necessary to understand which factors were associated with SSI. The aim of this study was to identify predictors of SSI and quantify the incidence of SSI in calcaneus fractures following open reduction and internal fixation (ORIF).
This retrospective study was performed at a level 1 trauma center from January 2014 to June in 2017. Data of adult patients with calcaneus fractures treated by ORIF were extracted from the electronic medical records. A total of 681 patients were collected. We reviewed the patients' demographics, characteristics of fracture, treatment-related variables, and indexes of laboratory examination. Univariate and multivariate logistic analysis models were performed respectively to determine independent predictors of SSI.
Sixty-six patients developed SSI in this study. The overall incidence of SSI after ORIF of calcaneus fracture was 9.7%, with 2.9% for deep infection and 6.8% for superficial SSI. Independent predictors of SSI identified by multivariate analysis were open fracture (odds ratio = 9.48, 95% CI = 4.53-19.85, P = 0.00007), high-energy injury (odds ratio = 2.07, 95% CI = 1.16-3.70, P = 0.01437), ASA class 3 or higher (odds ratio = 3.50, 95% CI = 1.18-10.37, P = 0.02401), and intraoperative temperature < 36.0 °C (odds ratio = 1.69, 95% CI = 1.13-2.28, P = 0.04410).
The SSI incidence was high (9.7%) for calcaneus fractures following ORIF. External fixation plays an important role in the treatment of severely displaced and depressed intra-articular or open calcaneus fractures. Increased ASA class and intraoperative hypothermia were associated with wound breakdown, and elaborative evaluation of fracture and soft-tissue damage was vitally necessary in this at-risk population.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Ankle</subject><subject>Calcaneus</subject><subject>Calcaneus - injuries</subject><subject>Calcaneus - surgery</subject><subject>Calcaneus fracture</subject><subject>Cardiovascular disease</subject><subject>Cohort analysis</subject><subject>Cohort Studies</subject><subject>Demography</subject><subject>Diabetes</subject><subject>Electronic medical records</subject><subject>Female</subject><subject>Fracture Fixation, Internal - adverse effects</subject><subject>Fracture Fixation, Internal - trends</subject><subject>Fractures</subject><subject>Fractures, Bone - diagnosis</subject><subject>Fractures, Bone - surgery</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Hypothermia</subject><subject>Incidence</subject><subject>Infections</subject><subject>Male</subject><subject>Medical records</subject><subject>Middle Aged</subject><subject>Multivariate analysis</subject><subject>Open Fracture Reduction - adverse effects</subject><subject>Open Fracture Reduction - trends</subject><subject>Orthopedics</subject><subject>Patients</subject><subject>Predictive Value of Tests</subject><subject>Retrospective Studies</subject><subject>Risk factors</subject><subject>Substance abuse treatment</subject><subject>Surgeons</subject><subject>Surgery</subject><subject>Surgical site infection</subject><subject>Surgical site infections</subject><subject>Surgical Wound Infection - diagnosis</subject><subject>Surgical Wound Infection - epidemiology</subject><subject>Trauma</subject><subject>Wounds</subject><subject>Young Adult</subject><issn>1749-799X</issn><issn>1749-799X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNpdklFrFDEQx4Motp5-AF8k4IsPrmY2yW72RZBi9aBQEAXfQi6ZXHPsbc4kW7hvb9arpZUwJCT_-TEz-RPyGtgHANV9zMAZqGYJYIw3xyfkHHoxNP0w_Hr64HxGXuS8Y0wyqcRzcsaZkEqBOCd5PdngcLJIzeToIaELtsSUafQ0z2kbrBlpDgVpmDzaEuJEjS-Y6PX39WW9pFVgzYRzpj4ZW-aE-T01NGFJMR-WlFukNt7EVGguszu-JM-8GTO-uttX5Ofllx8X35qr66_ri89XjRUDL03f9f3GwQBq06vanrHMiY1wohdcgOADQ_C1JKdAgWs97wCMUYN1xnsve74i6xPXRbPThxT2Jh11NEH_vYhpq00qwY6opTLK1WU7p0TbCiM4kyArFKT3bVtZn06sw7zZo7M4lWTGR9DHL1O40dt4q7tWSClVBby7A6T4e8Zc9D5ki-NYRxfnrFvgnZS8rY2uyNv_pLs4p6mOqqoqSon671UFJ5WtY84J_X0xwPRiD32yh15isYc-1pw3D7u4z_jnB_4HDm23XA</recordid><startdate>20181120</startdate><enddate>20181120</enddate><creator>Wang, Hui</creator><creator>Pei, Honglei</creator><creator>Chen, Meiyun</creator><creator>Wang, He</creator><general>BioMed Central</general><general>BMC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20181120</creationdate><title>Incidence and predictors of surgical site infection after ORIF in calcaneus fractures, a retrospective cohort study</title><author>Wang, Hui ; Pei, Honglei ; Chen, Meiyun ; Wang, He</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c493t-7677bd1918b78003ac0d4b4d4743414390e1ffecd8181d2f3611aa89cdafff573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Ankle</topic><topic>Calcaneus</topic><topic>Calcaneus - injuries</topic><topic>Calcaneus - surgery</topic><topic>Calcaneus fracture</topic><topic>Cardiovascular disease</topic><topic>Cohort analysis</topic><topic>Cohort Studies</topic><topic>Demography</topic><topic>Diabetes</topic><topic>Electronic medical records</topic><topic>Female</topic><topic>Fracture Fixation, Internal - adverse effects</topic><topic>Fracture Fixation, Internal - trends</topic><topic>Fractures</topic><topic>Fractures, Bone - diagnosis</topic><topic>Fractures, Bone - surgery</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Hypothermia</topic><topic>Incidence</topic><topic>Infections</topic><topic>Male</topic><topic>Medical records</topic><topic>Middle Aged</topic><topic>Multivariate analysis</topic><topic>Open Fracture Reduction - adverse effects</topic><topic>Open Fracture Reduction - trends</topic><topic>Orthopedics</topic><topic>Patients</topic><topic>Predictive Value of Tests</topic><topic>Retrospective Studies</topic><topic>Risk factors</topic><topic>Substance abuse treatment</topic><topic>Surgeons</topic><topic>Surgery</topic><topic>Surgical site infection</topic><topic>Surgical site infections</topic><topic>Surgical Wound Infection - diagnosis</topic><topic>Surgical Wound Infection - epidemiology</topic><topic>Trauma</topic><topic>Wounds</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Hui</creatorcontrib><creatorcontrib>Pei, Honglei</creatorcontrib><creatorcontrib>Chen, Meiyun</creatorcontrib><creatorcontrib>Wang, He</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Journal of orthopaedic surgery and research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Hui</au><au>Pei, Honglei</au><au>Chen, Meiyun</au><au>Wang, He</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Incidence and predictors of surgical site infection after ORIF in calcaneus fractures, a retrospective cohort study</atitle><jtitle>Journal of orthopaedic surgery and research</jtitle><addtitle>J Orthop Surg Res</addtitle><date>2018-11-20</date><risdate>2018</risdate><volume>13</volume><issue>1</issue><spage>293</spage><epage>293</epage><pages>293-293</pages><artnum>293</artnum><issn>1749-799X</issn><eissn>1749-799X</eissn><abstract>Occurrence of calcaneus fractures is on the up trend. Owing to its unique anatomical morphology and limited soft-tissue envelope, management of calcaneus fractures is a challenge to the orthopaedic surgeon, and surgical site infection (SSI) is one of the serious postoperative complications. In order to decrease the incidence of wound breakdown and improve clinical outcomes, it is necessary to understand which factors were associated with SSI. The aim of this study was to identify predictors of SSI and quantify the incidence of SSI in calcaneus fractures following open reduction and internal fixation (ORIF).
This retrospective study was performed at a level 1 trauma center from January 2014 to June in 2017. Data of adult patients with calcaneus fractures treated by ORIF were extracted from the electronic medical records. A total of 681 patients were collected. We reviewed the patients' demographics, characteristics of fracture, treatment-related variables, and indexes of laboratory examination. Univariate and multivariate logistic analysis models were performed respectively to determine independent predictors of SSI.
Sixty-six patients developed SSI in this study. The overall incidence of SSI after ORIF of calcaneus fracture was 9.7%, with 2.9% for deep infection and 6.8% for superficial SSI. Independent predictors of SSI identified by multivariate analysis were open fracture (odds ratio = 9.48, 95% CI = 4.53-19.85, P = 0.00007), high-energy injury (odds ratio = 2.07, 95% CI = 1.16-3.70, P = 0.01437), ASA class 3 or higher (odds ratio = 3.50, 95% CI = 1.18-10.37, P = 0.02401), and intraoperative temperature < 36.0 °C (odds ratio = 1.69, 95% CI = 1.13-2.28, P = 0.04410).
The SSI incidence was high (9.7%) for calcaneus fractures following ORIF. External fixation plays an important role in the treatment of severely displaced and depressed intra-articular or open calcaneus fractures. Increased ASA class and intraoperative hypothermia were associated with wound breakdown, and elaborative evaluation of fracture and soft-tissue damage was vitally necessary in this at-risk population.</abstract><cop>England</cop><pub>BioMed Central</pub><pmid>30458814</pmid><doi>10.1186/s13018-018-1003-y</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Adult Aged Ankle Calcaneus Calcaneus - injuries Calcaneus - surgery Calcaneus fracture Cardiovascular disease Cohort analysis Cohort Studies Demography Diabetes Electronic medical records Female Fracture Fixation, Internal - adverse effects Fracture Fixation, Internal - trends Fractures Fractures, Bone - diagnosis Fractures, Bone - surgery Hospitals Humans Hypothermia Incidence Infections Male Medical records Middle Aged Multivariate analysis Open Fracture Reduction - adverse effects Open Fracture Reduction - trends Orthopedics Patients Predictive Value of Tests Retrospective Studies Risk factors Substance abuse treatment Surgeons Surgery Surgical site infection Surgical site infections Surgical Wound Infection - diagnosis Surgical Wound Infection - epidemiology Trauma Wounds Young Adult |
title | Incidence and predictors of surgical site infection after ORIF in calcaneus fractures, a retrospective cohort study |
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