Phytochemical Compositions and Antioxidant Properties of Combined Funtumia africana and Abutilon mauritianum Extract (CFAE)

Medically active compounds in plants confer biological effects including antioxidant properties. This study evaluated the phytochemical content and in vitro antioxidant properties of combined Funtumia africana leaves and Abutilon mauritianum extract (CFAE). The 1,1-diphenyl-2-picrylhydrazyl (DPPH),...

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Bibliographic Details
Published in:Biology, medicine, & natural product chemistry (Online) medicine, & natural product chemistry (Online), 2022-07, Vol.11 (2), p.111-118
Main Authors: Uroko, Robert Ikechukwu, Chukwu, Charles Nnanna, Aaron, Chinomso Friday, Chidozie, Umezurike Benedict, Akachukwu, Doris, Atuh, Ndukwe Onyeani
Format: Article
Language:English
Subjects:
abutilon mauritianum
antioxidant activity
antioxidant vitamins
free radicals
funtumia africana
phytochemicals
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Summary:Medically active compounds in plants confer biological effects including antioxidant properties. This study evaluated the phytochemical content and in vitro antioxidant properties of combined Funtumia africana leaves and Abutilon mauritianum extract (CFAE). The 1,1-diphenyl-2-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP), thiobarbituric acid reactive substances (TBARS), total antioxidant capacity (TAC), and nitric oxide radical (NO.) scavenging capabilities were used as antioxidant assay models. The results of the phytochemical analysis showed that CFAE is rich in alkaloids, flavonoids, tannins, saponins, phenols and cardiac glycosides. The extract contains antioxidant vitamins A, C and E, vitamin E being the most abundant. The CFAE showed a dose-dependent TAC based on the observed FRAP, TBARS, and DPPH scavenging activity which could be attributed to the presence of phenolic compounds and vitamins E. These strongly suggest that CFAE is a potential source of phytochemicals and antioxidants which could be exploited in the food and pharmaceutical industries in production of potent nutraceuticals or therapeutically-important products.
ISSN:2089-6514
2540-9328
DOI:10.14421/biomedich.2022.112.111-118