Association Between Serum Ferritin Levels and Low Bone Mineral Density in Postmenopausal Osteoporosis Women

As women go through menopause, serum estrogen decreases, and ferritin increases. Ferritin is an essential component of the body, but many studies have stated that ferritin, which exceeds the normal physiological range, may potentially cause health problems in women. The aim of this study is to inves...

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Bibliographic Details
Published in:Acta medica Iranica 2019, Vol.57 (12), p.714
Main Authors: ALjeshi, Lama, Haddad, Shaden
Format: Article
Language:English
Subjects:
Biochemistry
Bone density
Bone mineral density
Ferritin
Fracture
Fractures
Homeostasis
Iron
Menopause
Metabolism
Osteoporosis
Pharmacy
Physiology
Postmenopausal women
Thyroid gland
Variables
Variance analysis
Womens health
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Summary:As women go through menopause, serum estrogen decreases, and ferritin increases. Ferritin is an essential component of the body, but many studies have stated that ferritin, which exceeds the normal physiological range, may potentially cause health problems in women. The aim of this study is to investigate the relationship between bone mineral density and serum ferritin levels in post-menopausal women and to evaluate serum ferritin levels as a potential biomarker for postmenopausal osteoporosis. Serum ferritin levels were measured in 62 postmenopausal women with low bone mineral density, and in 18 postmenopausal healthy control women using a standardized Enzyme-Linked Immune Sorbent Assay (ELISA) kit. Bone mineral density BMD was assessed at the lumbar spine and femoral neck. The mean serum ferritin level was significantly higher in the postmenopausal women with low BMD group (group 1) than in the normal control group (group 2), respectively (mean=262.69 vs. 181.44 ng/ml, (P
ISSN:0044-6025
1735-9694
DOI:10.18502/acta.v57i12.3468