Successful treatment of Mucor circinelloides in a Burn patient

•Mucormycosis is a rare disease, which has a poor prognosis among burn patients.•Successful management is a combination of antifungal treatment with extensive debridement.•Rapid identification and resistance testing of the Mucor circinelloides was pivotal in establishing the diagnosis. Mucormycosis...

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Published in:Burns open : an international open access journal for burn injuries 2022-04, Vol.6 (2), p.77-81
Main Authors: Abdelmonem, Reham, Backx, Matthijs, Vale, Lorna, Healy, Brendan, Williams, David
Format: Article
Language:English
Subjects:
Amphotericin B
Burn
Isavuconazole
Mucor circinelloides
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Summary:•Mucormycosis is a rare disease, which has a poor prognosis among burn patients.•Successful management is a combination of antifungal treatment with extensive debridement.•Rapid identification and resistance testing of the Mucor circinelloides was pivotal in establishing the diagnosis. Mucormycosis is a rare disease, which has a poor prognosis among burn patients with a reported mortality of 40–88%. We report on the survival of a 54-year-old male patient with burns of 50% of his total body surface area (TBSA) who survived despite rapid deterioration following cutaneous and probable systemic mucormycosis. A combination of antifungal treatment with extensive debridement and amputation likely resulted in the positive outcome in this case. The case highlights the importance of early diagnosis, antifungal treatment, and aggressive surgical management in burn patients with mucormycosis.
ISSN:2468-9122
2468-9122
DOI:10.1016/j.burnso.2022.02.005