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Efficacy and safety of atrial fibrillation ablation in heart failure patients with left ventricular ejection fraction less than 50
The efficacy of catheter ablation in patients with low cardiac function has been previously reported; however, only a few studies have included mid-range ejection fraction (mrEF). This study aimed to evaluate the efficacy and safety of atrial fibrillation (AF) ablation in patients with left ventricu...
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Published in: | Indian pacing and electrophysiology journal 2023-09, Vol.23 (5), p.135-141 |
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container_title | Indian pacing and electrophysiology journal |
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creator | Sakamoto, Yusuke Osanai, Hiroyuki Sakai, Yuichiro Sogo, Yoshiki Tanaka, Yuki Hiramatsu, Shotaro Matsumoto, Hikari Tomooka, Ken Arai, Kenji Watanabe, Takashi Ohguchi, Shioh Kanbara, Takahiro Nakashima, Yoshihito Asano, Hiroshi Ajioka, Masayoshi |
description | The efficacy of catheter ablation in patients with low cardiac function has been previously reported; however, only a few studies have included mid-range ejection fraction (mrEF). This study aimed to evaluate the efficacy and safety of atrial fibrillation (AF) ablation in patients with left ventricular ejection fraction (LVEF) |
doi_str_mv | 10.1016/j.ipej.2023.06.004 |
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This study retrospectively analyzed 79 patients (reduced ejection fraction [rEF]/mrEF, 38/41; paroxysmal/persistent, 37/42; heart failure hospitalizations within one year before ablation, 36 [45.6%]) who underwent the first ablation procedure at our hospital from April 2017 to December 2021. Radiofrequency ablation and cryoablation were performed for 69 and 10 patients, respectively.
Complications included pacemaker implantation for postoperative sick sinus syndrome in one patient and inguinal hematoma in one patient. Regarding efficacy, there were significant postoperative improvements in echocardiographic data, blood test values, and diuretic use. After a mean follow-up of 60 months, 86.1% patients had no AF recurrence. There were 9 heart failure hospitalizations (11.4%) and 5 all-cause deaths (6.3%); no significant differences were found between the rEF and mrEF groups. No significant predictors of AF recurrence were found in preoperative patient characteristics.
AF ablation in patients with LVEF <50% significantly improved cardiac and renal functions with few complications, resulting in a high non-recurrence rate and reduced heart failure.
•Study included 79 patients with left ventricular ejection fraction less than 50%.•Patients underwent catheter ablation for atrial fibrillation.•Ablation is effective and safe in patients with reduced left ventricular function including mid-range EF.</description><identifier>ISSN: 0972-6292</identifier><identifier>EISSN: 0972-6292</identifier><identifier>DOI: 10.1016/j.ipej.2023.06.004</identifier><identifier>PMID: 37385589</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Atrial fibrillation ; Catheter ablation ; Heart failure ; Left ventricular ejection fraction ; Original ; Renal function</subject><ispartof>Indian pacing and electrophysiology journal, 2023-09, Vol.23 (5), p.135-141</ispartof><rights>2023 Indian Heart Rhythm Society</rights><rights>Copyright © 2023 Indian Heart Rhythm Society. Published by Elsevier B.V. All rights reserved.</rights><rights>2023 Indian Heart Rhythm Society. Published by Elsevier B.V. 2023 Indian Heart Rhythm Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4374-b0a77edf565ee03cf1091bc2fb23aee57c5dcec9cf9010476b5cce27d09386ca3</citedby><cites>FETCH-LOGICAL-c4374-b0a77edf565ee03cf1091bc2fb23aee57c5dcec9cf9010476b5cce27d09386ca3</cites><orcidid>0000-0002-5959-1445</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491960/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0972629223000748$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,3549,27924,27925,45780,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37385589$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sakamoto, Yusuke</creatorcontrib><creatorcontrib>Osanai, Hiroyuki</creatorcontrib><creatorcontrib>Sakai, Yuichiro</creatorcontrib><creatorcontrib>Sogo, Yoshiki</creatorcontrib><creatorcontrib>Tanaka, Yuki</creatorcontrib><creatorcontrib>Hiramatsu, Shotaro</creatorcontrib><creatorcontrib>Matsumoto, Hikari</creatorcontrib><creatorcontrib>Tomooka, Ken</creatorcontrib><creatorcontrib>Arai, Kenji</creatorcontrib><creatorcontrib>Watanabe, Takashi</creatorcontrib><creatorcontrib>Ohguchi, Shioh</creatorcontrib><creatorcontrib>Kanbara, Takahiro</creatorcontrib><creatorcontrib>Nakashima, Yoshihito</creatorcontrib><creatorcontrib>Asano, Hiroshi</creatorcontrib><creatorcontrib>Ajioka, Masayoshi</creatorcontrib><title>Efficacy and safety of atrial fibrillation ablation in heart failure patients with left ventricular ejection fraction less than 50</title><title>Indian pacing and electrophysiology journal</title><addtitle>Indian Pacing Electrophysiol J</addtitle><description>The efficacy of catheter ablation in patients with low cardiac function has been previously reported; however, only a few studies have included mid-range ejection fraction (mrEF). This study aimed to evaluate the efficacy and safety of atrial fibrillation (AF) ablation in patients with left ventricular ejection fraction (LVEF) < 50%.
This study retrospectively analyzed 79 patients (reduced ejection fraction [rEF]/mrEF, 38/41; paroxysmal/persistent, 37/42; heart failure hospitalizations within one year before ablation, 36 [45.6%]) who underwent the first ablation procedure at our hospital from April 2017 to December 2021. Radiofrequency ablation and cryoablation were performed for 69 and 10 patients, respectively.
Complications included pacemaker implantation for postoperative sick sinus syndrome in one patient and inguinal hematoma in one patient. Regarding efficacy, there were significant postoperative improvements in echocardiographic data, blood test values, and diuretic use. After a mean follow-up of 60 months, 86.1% patients had no AF recurrence. There were 9 heart failure hospitalizations (11.4%) and 5 all-cause deaths (6.3%); no significant differences were found between the rEF and mrEF groups. No significant predictors of AF recurrence were found in preoperative patient characteristics.
AF ablation in patients with LVEF <50% significantly improved cardiac and renal functions with few complications, resulting in a high non-recurrence rate and reduced heart failure.
•Study included 79 patients with left ventricular ejection fraction less than 50%.•Patients underwent catheter ablation for atrial fibrillation.•Ablation is effective and safe in patients with reduced left ventricular function including mid-range EF.</description><subject>Atrial fibrillation</subject><subject>Catheter ablation</subject><subject>Heart failure</subject><subject>Left ventricular ejection fraction</subject><subject>Original</subject><subject>Renal function</subject><issn>0972-6292</issn><issn>0972-6292</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNp9kk1v1DAQhiMEoqXwBzggH7lsmPgjiSUkhKoClSpxgbM1ccZdR95ksbOL9sovx7tZqvbCyePxO8-MZ6Yo3lZQVlDVH4bSb2koOXBRQl0CyGfFJeiGr2qu-fNH9kXxKqUBgCupm5fFhWhEq1SrL4s_N855i_bAcOxZQkfzgU2O4Rw9BuZ8F30IOPtpZNidDT-yNWGcmUMfdpHYNvtpnBP77ec1C-Rmts_36O0uYGQ0kD0FuoiLESglNq9xZApeFy8chkRvzudV8fPLzY_rb6u7719vrz_frawUjVx1gE1DvVO1IgJhXQW66ix3HRdIpBqrektWW6ehAtnUnbKWeNODFm1tUVwVtwu3n3Aw2-g3GA9mQm9Ojinem_wnbwMZpSUH2SpErKSEtkPRkuJd62T2CpdZnxbWdtdtKOfNn8XwBPr0ZfRrcz_tTa5MV7qGTHh_JsTp147SbDY-Wcq9HmnaJcNbwVULCmSW8kVq45RSJPeQpwJz3AQzmOMmmOMmGKgNnILePa7wIeTf6LPg4yKg3PO9p2iSzUO01PuYx5Wb4v_H_wupjMf9</recordid><startdate>20230901</startdate><enddate>20230901</enddate><creator>Sakamoto, Yusuke</creator><creator>Osanai, Hiroyuki</creator><creator>Sakai, Yuichiro</creator><creator>Sogo, Yoshiki</creator><creator>Tanaka, Yuki</creator><creator>Hiramatsu, Shotaro</creator><creator>Matsumoto, Hikari</creator><creator>Tomooka, Ken</creator><creator>Arai, Kenji</creator><creator>Watanabe, Takashi</creator><creator>Ohguchi, Shioh</creator><creator>Kanbara, Takahiro</creator><creator>Nakashima, Yoshihito</creator><creator>Asano, Hiroshi</creator><creator>Ajioka, Masayoshi</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-5959-1445</orcidid></search><sort><creationdate>20230901</creationdate><title>Efficacy and safety of atrial fibrillation ablation in heart failure patients with left ventricular ejection fraction less than 50</title><author>Sakamoto, Yusuke ; Osanai, Hiroyuki ; Sakai, Yuichiro ; Sogo, Yoshiki ; Tanaka, Yuki ; Hiramatsu, Shotaro ; Matsumoto, Hikari ; Tomooka, Ken ; Arai, Kenji ; Watanabe, Takashi ; Ohguchi, Shioh ; Kanbara, Takahiro ; Nakashima, Yoshihito ; Asano, Hiroshi ; Ajioka, Masayoshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4374-b0a77edf565ee03cf1091bc2fb23aee57c5dcec9cf9010476b5cce27d09386ca3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Atrial fibrillation</topic><topic>Catheter ablation</topic><topic>Heart failure</topic><topic>Left ventricular ejection fraction</topic><topic>Original</topic><topic>Renal function</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sakamoto, Yusuke</creatorcontrib><creatorcontrib>Osanai, Hiroyuki</creatorcontrib><creatorcontrib>Sakai, Yuichiro</creatorcontrib><creatorcontrib>Sogo, Yoshiki</creatorcontrib><creatorcontrib>Tanaka, Yuki</creatorcontrib><creatorcontrib>Hiramatsu, Shotaro</creatorcontrib><creatorcontrib>Matsumoto, Hikari</creatorcontrib><creatorcontrib>Tomooka, Ken</creatorcontrib><creatorcontrib>Arai, Kenji</creatorcontrib><creatorcontrib>Watanabe, Takashi</creatorcontrib><creatorcontrib>Ohguchi, Shioh</creatorcontrib><creatorcontrib>Kanbara, Takahiro</creatorcontrib><creatorcontrib>Nakashima, Yoshihito</creatorcontrib><creatorcontrib>Asano, Hiroshi</creatorcontrib><creatorcontrib>Ajioka, Masayoshi</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>Indian pacing and electrophysiology journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sakamoto, Yusuke</au><au>Osanai, Hiroyuki</au><au>Sakai, Yuichiro</au><au>Sogo, Yoshiki</au><au>Tanaka, Yuki</au><au>Hiramatsu, Shotaro</au><au>Matsumoto, Hikari</au><au>Tomooka, Ken</au><au>Arai, Kenji</au><au>Watanabe, Takashi</au><au>Ohguchi, Shioh</au><au>Kanbara, Takahiro</au><au>Nakashima, Yoshihito</au><au>Asano, Hiroshi</au><au>Ajioka, Masayoshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Efficacy and safety of atrial fibrillation ablation in heart failure patients with left ventricular ejection fraction less than 50</atitle><jtitle>Indian pacing and electrophysiology journal</jtitle><addtitle>Indian Pacing Electrophysiol J</addtitle><date>2023-09-01</date><risdate>2023</risdate><volume>23</volume><issue>5</issue><spage>135</spage><epage>141</epage><pages>135-141</pages><issn>0972-6292</issn><eissn>0972-6292</eissn><abstract>The efficacy of catheter ablation in patients with low cardiac function has been previously reported; however, only a few studies have included mid-range ejection fraction (mrEF). This study aimed to evaluate the efficacy and safety of atrial fibrillation (AF) ablation in patients with left ventricular ejection fraction (LVEF) < 50%.
This study retrospectively analyzed 79 patients (reduced ejection fraction [rEF]/mrEF, 38/41; paroxysmal/persistent, 37/42; heart failure hospitalizations within one year before ablation, 36 [45.6%]) who underwent the first ablation procedure at our hospital from April 2017 to December 2021. Radiofrequency ablation and cryoablation were performed for 69 and 10 patients, respectively.
Complications included pacemaker implantation for postoperative sick sinus syndrome in one patient and inguinal hematoma in one patient. Regarding efficacy, there were significant postoperative improvements in echocardiographic data, blood test values, and diuretic use. After a mean follow-up of 60 months, 86.1% patients had no AF recurrence. There were 9 heart failure hospitalizations (11.4%) and 5 all-cause deaths (6.3%); no significant differences were found between the rEF and mrEF groups. No significant predictors of AF recurrence were found in preoperative patient characteristics.
AF ablation in patients with LVEF <50% significantly improved cardiac and renal functions with few complications, resulting in a high non-recurrence rate and reduced heart failure.
•Study included 79 patients with left ventricular ejection fraction less than 50%.•Patients underwent catheter ablation for atrial fibrillation.•Ablation is effective and safe in patients with reduced left ventricular function including mid-range EF.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>37385589</pmid><doi>10.1016/j.ipej.2023.06.004</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-5959-1445</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Atrial fibrillation Catheter ablation Heart failure Left ventricular ejection fraction Original Renal function |
title | Efficacy and safety of atrial fibrillation ablation in heart failure patients with left ventricular ejection fraction less than 50 |
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