Survival and Durability of Minimally Invasive Mitral Valve Repair: Insights from Different Repair Techniques

This study evaluates the long-term outcomes of minimally invasive mitral valve repair (MIMVR) in patients with degenerative mitral regurgitation, focusing on survival, mitral valve repair failure, and re-operation rates. A cohort of patients undergoing three primary repair techniques-quadrangular re...

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Bibliographic Details
Published in:Medical sciences (Basel) 2024-09, Vol.12 (3), p.46
Main Authors: Iaccarino, Alessandra, Giambuzzi, Ilaria, Galbiati, Denise, Cuko, Enea, Droandi, Ginevra, Forcina, Sara, Kushta, Eraldo, Basciu, Alessio, Barbone, Alessandro, Fumero, Andrea, Torracca, Lucia
Format: Article
Language:English
Subjects:
Aged
artificial chordae
edge-to-edge
Female
Humans
Hypothesis testing
Male
Middle Aged
mini-thoracotomy mitral valve repair
minimally invasive mitral valve repair
Minimally Invasive Surgical Procedures
Mitral Valve - surgery
Mitral Valve Insufficiency - surgery
mitral valve repair
Mortality
Ostomy
Patients
quadrangular resection
Reoperation
Surgery
Surgical techniques
Treatment Outcome
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Summary:This study evaluates the long-term outcomes of minimally invasive mitral valve repair (MIMVR) in patients with degenerative mitral regurgitation, focusing on survival, mitral valve repair failure, and re-operation rates. A cohort of patients undergoing three primary repair techniques-quadrangular resection, edge-to-edge repair, and artificial chordae implantation-was analyzed using time-to-event methods. The overall survival rates at 1, 10, and 20 years were high and comparable among the techniques, indicating effective long-term benefits of MIMVR. However, freedom from recurrence of moderate mitral regurgitation (MR) ≥ 2 was significantly higher in the quadrangular resection and edge-to-edge groups compared to the artificial chordae group. No significant differences were observed for recurrent MR ≥ 3. Re-operation rates were low and similar across all techniques, underscoring the durability of MIMVR. Pre-discharge residual MR ≥ 2 was identified as a strong predictor of long-term repair failure. These findings confirm the effectiveness of MIMVR, with all techniques demonstrating excellent long-term survival and durability.
ISSN:2076-3271
2076-3271
DOI:10.3390/medsci12030046