Waning Antibody Responses in Asymptomatic and Symptomatic SARS-CoV-2 Infection

We investigated the kinetics of severe acute respiratory syndrome coronavirus 2 neutralizing antibodies in 7 asymptomatic persons and 11 patients with pneumonia. The geometric mean titer of neutralizing antibodies declined from 219.4 at 2 months to 143.7 at 5 months after infection, indicating a wan...

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Bibliographic Details
Published in:Emerging infectious diseases 2021-01, Vol.27 (1), p.327-329
Main Authors: Choe, Pyoeng Gyun, Kang, Chang Kyung, Suh, Hyeon Jeong, Jung, Jongtak, Song, Kyoung-Ho, Bang, Ji Hwan, Kim, Eu Suk, Kim, Hong Bin, Park, Sang Won, Kim, Nam Joong, Park, Wan Beom, Oh, Myoung-Don
Format: Article
Language:English
Subjects:
Antibodies
Antibodies, Neutralizing - blood
Antibodies, Viral - blood
Antibody Formation
Asymptomatic
Coronaviruses
COVID-19
COVID-19 - immunology
Disease
ELISA
Epidemics
Expedited
Hospitals
Humans
Identification and classification
Immune response
Infections
neutralizing antibodies
Observations
Physiological aspects
Pneumonia
Research Letter
respiratory infections
SARS-CoV-2
SARS-CoV-2 - immunology
Severe acute respiratory syndrome coronavirus 2
South Korea
Viral antibodies
Waning Antibody Responses in Asymptomatic and Symptomatic SARS-CoV-2 Infection
waning immunity
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Summary:We investigated the kinetics of severe acute respiratory syndrome coronavirus 2 neutralizing antibodies in 7 asymptomatic persons and 11 patients with pneumonia. The geometric mean titer of neutralizing antibodies declined from 219.4 at 2 months to 143.7 at 5 months after infection, indicating a waning antibody response.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid2701.203515