Cardiovascular risk and all-cause mortality in a memory clinic population

The prevalence of atherosclerotic cardiovascular diseases and its associated mortality are increasing worldwide. In persons with cognitive impairment, the potential benefits from treatment of hypertension and dyslipidaemia may be overestimated due to competing mortality risks related to cognitive im...

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Bibliographic Details
Published in:Cerebral circulation - cognition and behavior 2024, Vol.6, p.100346, Article 100346
Main Authors: Nijskens, Charlotte, Wiersinga, Julia, Henstra, Marieke, Rhodius, Hanneke, Muller, Majon
Format: Article
Language:English
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Summary:The prevalence of atherosclerotic cardiovascular diseases and its associated mortality are increasing worldwide. In persons with cognitive impairment, the potential benefits from treatment of hypertension and dyslipidaemia may be overestimated due to competing mortality risks related to cognitive impairment. We therefore aim to explore the association between cardiovascular risk and all-cause mortality in a memory clinic population, and whether this relation is modified by cognitive and physical performance. All patients from the Amsterdam Ageing Cohort who visited the memory clinic were included. Cardiovascular risk was assessed with the SCORE2-OP, a validated instrument to estimate 5- and 10-year risk for non-fatal myocardial infarction, non-fatal stroke and cardiovascular mortality in persons aged ≥70 years. A 10-year risk of
ISSN:2666-2450
2666-2450
DOI:10.1016/j.cccb.2024.100346