Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans

Corynebacterium ulcerans infection is emerging in humans. We conducted phylogenetic analyses of C. ulcerans and C. diptheriae, which revealed diverse diphtheria toxin in C. ulcerans. Diphtheria toxin diversification could decrease effectiveness of diphtheria toxoid vaccine and diphtheria antitoxin f...

Full description

Saved in:
Bibliographic Details
Published in:Emerging infectious diseases 2019-11, Vol.25 (11), p.2122-2123
Main Authors: Otsuji, Ken, Fukuda, Kazumasa, Ogawa, Midori, Saito, Mitsumasa
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Analysis
bacteria
Biological products
Corynebacterium - genetics
Corynebacterium ulcerans
Death
Diphtheria
Diphtheria - epidemiology
Diphtheria - microbiology
Diphtheria - prevention & control
Diphtheria toxin
Diphtheria Toxin - chemistry
Diphtheria Toxin - genetics
Diphtheria Toxoid
diversity
Genes
Genetic aspects
Genetic Variation
Health aspects
Humans
Infection
Japan
Japan - epidemiology
Mutation
Mutation and Diversity of Diphtheria Toxin in
Phylogeny
Research Letter
RNA, Ribosomal, 16S - genetics
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Corynebacterium ulcerans infection is emerging in humans. We conducted phylogenetic analyses of C. ulcerans and C. diptheriae, which revealed diverse diphtheria toxin in C. ulcerans. Diphtheria toxin diversification could decrease effectiveness of diphtheria toxoid vaccine and diphtheria antitoxin for preventing and treating illnesses caused by this bacterium.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid2511.181455